Regulation of hepcidin/iron-signalling pathway interactions by commensal bifidobateria plays an important role for the inhibition of metaflammation-related biomarkers

•Commensal bifidobacteria inhibit the NF-κB-mediated transcriptional activation of metabolic disorder-causing factors (IL-1β and IL-6).•They interfere with the iron-IL-6-hepcidin axis, which positively regulates NF-κB activity, thereby rescuing metaflammation markers. Increased concentration of ferr...

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