Serum soluble sialic acid‐binding immunoglobulin‐like lectin‐7 concentration as an indicator of liver macrophage activation and advanced fibrosis in patients with non‐alcoholic fatty liver disease

Aim Non‐alcoholic fatty liver disease (NAFLD) is a leading cause of liver disease worldwide. Because liver fibrosis is associated with the long‐term prognosis of patients with NAFLD, there is an urgent need for non‐invasive markers of liver fibrosis. Sialic acid‐binding immunoglobulin‐like lectin‐7...

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Veröffentlicht in:	Hepatology research 2020-04, Vol.50 (4), p.466-477
Hauptverfasser:	Sakamoto, Yuzuru, Yoshio, Sachiyo, Doi, Hiroyoshi, Kawai, Hironari, Shimagaki, Tomonari, Mori, Taizo, Matsuda, Michitaka, Aoki, Yoshihiko, Osawa, Yosuke, Yoshida, Yuji, Arai, Taeang, Itokawa, Norio, Ito, Takanori, Seko, Yuya, Yamaguchi, Kanji, Itoh, Yoshihito, Mise, Yoshihiro, Saiura, Akio, Taketomi, Akinobu, Kanto, Tatsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	CCR2 protein CD163 antigen Cell activation Fatty liver Fibrosis Immunoglobulins Immunomodulation Inflammation Liver diseases macrophage Macrophages Monocyte chemoattractant protein 1 Monocytes non‐alcoholic fatty liver disease Serum levels sialic acid‐binding immunoglobulin‐like lectin‐7
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