Comparison of CE- and MPS-based analyses of forensic markers in a single cell after whole genome amplification

•Both cultured and freshly drawn blood cells were separated and tested to simulate low copy number sample genotyping.•The ForenSeq DNA Signature Prep Kit was used to evaluate MPS performance following WGA.•Depth of coverage, allele balance and sequence coverage ratio were investigated on the MPS pla...

Ausführliche Beschreibung