Pharmacological Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Alleviates Carbon Tetrachloride-Induced Liver Fibrosis in Mice

Background: Transient receptor potential vanilloid 4 (TRPV4) is a member of the TRP channel family and is involved in diverse physiological and pathological processes. Accumulating evidence from in vitro studies indicates that TRPV4 has a potential role in liver fibrosis, but its precise role in the...

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Veröffentlicht in:	Journal of Nippon Medical School 2019/10/15, Vol.86(5), pp.258-262
Hauptverfasser:	Fu, Jie, Du, Huihui, Zhang, Xiao, Xu, Xundi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carbon Tetrachloride in vivo Liver - pathology Liver Cirrhosis - chemically induced Liver Cirrhosis - drug therapy Liver Cirrhosis - pathology liver fibrosis Male Mice, Inbred C57BL TRPV Cation Channels - antagonists & inhibitors TRPV Cation Channels - metabolism TRPV4
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