Thiolated Nanoparticles Overcome the Mucus Barrier and Epithelial Barrier for Oral Delivery of Insulin

Oral administration is an ideal alternative for drug delivery due to its convenience and safety. However, oral protein delivery is limited by biological barriers such as the mucus barrier and epithelial barrier, which hamper drugs from entering the blood successfully. Here we presented PC6/CS NPs, a...

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Veröffentlicht in:Molecular pharmaceutics 2020-01, Vol.17 (1), p.239-250
Hauptverfasser: Zhou, Shurong, Deng, Hailiang, Zhang, Yang, Wu, Peiyao, He, Bing, Dai, Wenbing, Zhang, Hua, Zhang, Qiang, Zhao, Rongsheng, Wang, Xueqing
Format: Artikel
Sprache:eng
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