Genistein protects against amyloid‐beta‐induced toxicity in SH‐SY5Y cells by regulation of Akt and Tau phosphorylation

Alzheimer's disease is a neurodegenerative disorder characterized by extracellular deposition of amyloid‐β (Aβ) peptide and hyperphosphorylation of Tau protein, which ultimately leads to the formation of intracellular neurofibrillary tangles and cell death. Increasing evidence indicates that ge...

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Veröffentlicht in:Phytotherapy research 2020-04, Vol.34 (4), p.796-807
Hauptverfasser: Petry, Fernanda dos Santos, Coelho, Bárbara Paranhos, Gaelzer, Mariana Maier, Kreutz, Fernando, Guma, Fátima Theresinha Costa Rodrigues, Salbego, Christianne Gazzana, Trindade, Vera Maria Treis
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