A general strategy to develop cell permeable and fluorogenic probes for multicolour nanoscopy

Live-cell fluorescence nanoscopy is a powerful tool to study cellular biology on a molecular scale, yet its use is held back by the paucity of suitable fluorescent probes. Fluorescent probes based on regular fluorophores usually suffer from a low cell permeability and an unspecific background signal...

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Veröffentlicht in:Nature chemistry 2020-02, Vol.12 (2), p.165-172
Hauptverfasser: Wang, Lu, Tran, Mai, D’Este, Elisa, Roberti, Julia, Koch, Birgit, Xue, Lin, Johnsson, Kai
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Sprache:eng
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