Biochemical and structural analyses of the nucleosome containing human histone H2A.J

Histone H2A.J, a histone H2A variant conserved in mammals, may function in the expression of genes related to inflammation and cell proliferation. In the present study, we purified the human histone H2A.J variant and found that H2A.J is efficiently incorporated into the nucleosome in vitro. H2A.J fo...

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Veröffentlicht in:	Journal of biochemistry (Tokyo) 2020-04, Vol.167 (4), p.419-427
Hauptverfasser:	Tanaka, Hiroki, Sato, Shoko, Koyama, Masako, Kujirai, Tomoya, Kurumizaka, Hitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Histones - chemistry Histones - isolation & purification Histones - metabolism Humans Models, Molecular Nucleosomes - chemistry Nucleosomes - metabolism Recombinant Proteins - chemistry Recombinant Proteins - metabolism Temperature
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