Cardamonin induces immune responses and enhances survival rate in WEHI‐3 cell–generated mouse leukemia in vivo

Cardamonin, a monomeric alkaloid, is isolated from Alpinia conchigera Griff and other natural plants. Recently, it has been focused on its anticancer activities, and no information showing its immune effects on leukemia mice was reported. In this study, we investigated the immune effects of cardamon...

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Veröffentlicht in:	Environmental toxicology 2020-04, Vol.35 (4), p.457-467
Hauptverfasser:	Liao, Nien‐Chieh, Shih, Yung‐Luen, Ho, Ming‐Tak, Lu, Tai‐Jung, Lee, Ching‐Hsiao, Peng, Shu‐Fen, Leu, Sy‐Jye, Chung, Jing‐Gung
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticancer properties Antigens, CD19 - blood Antineoplastic Agents, Phytogenic - pharmacology BLAB/c mice Blood cells Body weight cardamonin CD11b antigen CD19 antigen CD3 antigen Cell Line, Tumor Cell Proliferation - drug effects Chalcones - pharmacology Dose-Response Relationship, Drug Flow cytometry Leukemia Leukemia, Experimental - drug therapy Leukemia, Experimental - immunology Leukocytes Leukocytes (mononuclear) Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - immunology Lymphocytes B macrophage phagocytosis Macrophages Macrophages - drug effects Macrophages - immunology Male Mice Mice, Inbred BALB C mouse leukemia WEHI‐3 cells Peripheral blood mononuclear cells Phagocytes Phagocytosis Phagocytosis - drug effects Phagocytosis - immunology Reagents Survival Survival Rate
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