Triazolecarbaldehyde Reagents for One‐Step N‐Terminal Protein Modification

Site‐specific modification of peptides and proteins is a key aspect of protein engineering. We developed a method for modification of the N terminus of proteins using 1H‐1,2,3‐triazole‐4‐carbaldehyde (TA4C) derivatives, which can be prepared in one step. The N‐terminal specific labeling of bioactive...

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