LncRNA MEG3 inhibits the progression of prostate cancer by facilitating H3K27 trimethylation of EN2 through binding to EZH2

This study aims to study the effects of intra-nuclear lncRNA MEG3 on the progression of prostate cancer and the underlying mechanisms. Expressions of relative molecules were detected by Quantitative real time PCR (qRT-PCR) and western blot. Chromatin immunoprecipitation and RNA immunoprecipitation (...

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Veröffentlicht in:Journal of biochemistry (Tokyo) 2020-03, Vol.167 (3), p.295-301
Hauptverfasser: Zhou, Yaojun, Yang, Hongqiong, Xia, Wei, Cui, Li, Xu, Renfang, Lu, Hao, Xue, Dong, Tian, Zinong, Ding, Tao, Cao, Yunjie, Shi, Qianqian, He, Xiaozhou
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Sprache:eng
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