Amelioration of thioacetamide-induced hepatic encephalopathy in rats by low-dose gamma irradiation

Brain affection is a common symptom of liver insufficiency. This study aimed to evaluate the role of low-dose γ irradiation (LDR) as a potential therapeutic agent in thioacetamide (TAA)-induced hepatic encephalopathy (HE) in rats. Effects of local and whole-body irradiation (0.5 Gy) on rat brain/liv...

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Veröffentlicht in:	Environmental science and pollution research international 2020-01, Vol.27 (1), p.334-343
Hauptverfasser:	El-Latif El-Ghazaly, Mona Abd, Rashed, Engy Refaat, Shafey, Ghada Mahmoud, Zaki, Hala Fahmy, Attia, Amina Salem
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Alanine Alanine transaminase Alanine Transaminase - blood Ammonia Animals Apoptosis Aspartate Aminotransferases - blood Aspartate transaminase Brain Brain - drug effects Chemical compounds Disease Models, Animal Environmental science Evaluation Fibrosis Gamma irradiation Gamma Rays Glutathione Glutathione - metabolism Glutathione peroxidase Hepatic encephalopathy Hepatic Encephalopathy - chemically induced IL-1β Inflammation Interleukin-1beta Interleukins Irradiation Liver Liver - drug effects Liver Function Tests Male Malondialdehyde Malondialdehyde - metabolism Muscles Oxidation-Reduction Oxidative stress Oxidative Stress - drug effects Peroxidase Pharmacology Radiation dosage Rats Rats, Wistar Rodents Smooth muscle Thioacetamide Thioacetamide - toxicity Transaminase Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Tumor necrosis factor-α
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