Enhanced cellular uptake and nuclear accumulation of drug-peptide nanomedicines prepared by enzyme-instructed self-assembly

Subcellular delivery of nanomedicines has emerged as a promising approach to enhance the therapeutic efficacy of anticancer drugs. Nuclear accumulation of anticancer drugs are essential for its therapeutic efficacy because their targets are generally located within the nucleus. However, strategies f...

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Veröffentlicht in:	Journal of controlled release 2020-01, Vol.317, p.109-117
Hauptverfasser:	Liang, Chunhui, Yan, Xiaorong, Zhang, Renshu, Xu, Tengyan, Zheng, Debing, Tan, Zhaoqi, Chen, Yaoxia, Gao, Zhengfeng, Wang, Ling, Li, Xingyi, Yang, Zhimou
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-cancer Enzyme Nuclear accumulation Peptide Self-assembly
Online-Zugang:	Volltext
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