Improving the barrier function of damaged cultured urothelium using chondroitin sulfate

Aims To determine whether glycosaminoglycan (GAG) replenishment is able to improve recovery of a deficient urothelial barrier, chondroitin sulfate (CS) instillations were tested using an in vitro model. Porcine urothelial cells (Ucells) were terminally differentiated in culture conditions to constru...

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Veröffentlicht in:	Neurourology and urodynamics 2020-02, Vol.39 (2), p.558-564
Hauptverfasser:	Rozenberg, Boy. B., Janssen, D. A. W., Jansen, C. F. J., Schalken, J. A., Heesakkers, J. P. F. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell culture Cell differentiation Chondroitin sulfate chondroitin sulfates Cystitis Glycosaminoglycans interstitial permeability Protamine Tight junctions Urothelium
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