C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4

Unlike the broad spectrum efficacies in wiping the malignant cells out, application of vincristine (VCR) in acute lymphoblastic leukemia (ALL) therapeutic protocol is partially restricted due to its high frequent resistant rate. Although several mechanisms have been enumerated for VCR resistance, to...

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Veröffentlicht in:	European journal of pharmacology 2020-03, Vol.870, p.172821-172821, Article 172821
Hauptverfasser:	Sheikh‐Zeineddini, Negar, Safaroghli-azar, Ava, Salari, Sina, Bashash, Davood
Format:	Artikel
Sprache:	eng
Schlagworte:	10058-F4 Acute lymphoblastic leukemia Autophagy c-Myc Vincristine resistance
Online-Zugang:	Volltext
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