The health and economic burden of osteoporotic fractures in Singapore and the potential impact of increasing treatment rates through more pharmacological options
Purpose This study aims to estimate the health and economic burden of osteoporosis in Singapore from 2017 to 2035, and to quantify the impact of increasing the treatment rate of osteoporosis. Methods Population forecast data of women and men aged 50 and above in Singapore from 2017 to 2035 was used...
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| Veröffentlicht in: | Archives of osteoporosis 2019-12, Vol.14 (1), p.114-114, Article 114 |
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| container_title | Archives of osteoporosis |
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| creator | Chandran, Manju Lau, Tang Ching Gagnon-Arpin, Isabelle Dobrescu, Alexandru Li, Wenshan Leung, Man Yee Mallory Patil, Narendra Zhao, Zhongyun |
| description | Purpose
This study aims to estimate the health and economic burden of osteoporosis in Singapore from 2017 to 2035, and to quantify the impact of increasing the treatment rate of osteoporosis.
Methods
Population forecast data of women and men aged 50 and above in Singapore from 2017 to 2035 was used along with prevalence rates of osteoporosis to project the osteoporosis population over time. The population projections by sex and age group were used along with osteoporotic fracture incidence rates by fracture type (hip, vertebral, other), and average direct and indirect costs per case to forecast the number of fractures, the total direct health care costs, and the total indirect costs due to fractures in Singapore. Data on treatment rates and effects were used to model the health and economic impact of increasing treatment rate of osteoporosis, using different hypothetical levels.
Results
Between 2017 and 2035, the incidence of osteoporotic fractures is projected to increase from 15,267 to 24,104 (a 57.9% increase) F 10,717 to 17,225 (a 60.7% increase) and M 4550 to 6878 (a 51.2% increase). The total economic burden (including direct costs and indirect costs to society) associated with these fractures is estimated at S$183.5 million in 2017 and is forecasted to grow to S$289.6 million by 2035. However, increasing the treatment rate for osteoporosis could avert up to 29,096 fractures over the forecast period (2017–2035), generating cumulative total cost savings of up to S$330.6 million.
Conclusion
Efforts to improve the detection, diagnosis, and treatment of osteoporosis are necessary to reduce the growing clinical, economic, and societal burden of fractures in Singapore. |
| doi_str_mv | 10.1007/s11657-019-0664-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2319194438</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2319194438</sourcerecordid><originalsourceid>FETCH-LOGICAL-c377t-124ca4974af52e84895197ed3917255eab9e9643f220e738b4d4d2ca86765cb43</originalsourceid><addsrcrecordid>eNp9kb1u3iAUhlHVqvlpL6BLxdjFCX8GM1ZR2kaKlKHpjDA-_kxkgwt4yOXkTov7JRkzccR53kc6ehH6QskFJURdZkplqxpCdUOkFI14h05pJ1nDWyrev86MnaCznB8IkYS28iM64VQpLgQ7RU_3E-AJ7FwmbMOAwcUQF-9wv6UBAo4jjrlAXGOKpX6PybqyJcjYB_zbh4OtG_gfLdW0xgKheDtjv6yV3PM-uAQ2VxaXOpSlEjjZUh1lSnE7THjZHetk02JdnOPBu2qIa_Ex5E_ow2jnDJ-f33P058f1_dWv5vbu583V99vGcaVKQ5lwVmgl7Ngy6ESnW6oVDFxTxdoWbK9BS8FHxggo3vViEANztpNKtq4X_Bx9O3rXFP9ukItZfHYwzzZA3LJhnGqqheBdRekRdSnmnGA0a_KLTY-GErM3Y47NmNqM2Zsxu_7rs37rFxheEy9VVIAdgVxX4QDJPMQthXryG9Z_Et6cuQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2319194438</pqid></control><display><type>article</type><title>The health and economic burden of osteoporotic fractures in Singapore and the potential impact of increasing treatment rates through more pharmacological options</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Chandran, Manju ; Lau, Tang Ching ; Gagnon-Arpin, Isabelle ; Dobrescu, Alexandru ; Li, Wenshan ; Leung, Man Yee Mallory ; Patil, Narendra ; Zhao, Zhongyun</creator><creatorcontrib>Chandran, Manju ; Lau, Tang Ching ; Gagnon-Arpin, Isabelle ; Dobrescu, Alexandru ; Li, Wenshan ; Leung, Man Yee Mallory ; Patil, Narendra ; Zhao, Zhongyun</creatorcontrib><description>Purpose
This study aims to estimate the health and economic burden of osteoporosis in Singapore from 2017 to 2035, and to quantify the impact of increasing the treatment rate of osteoporosis.
Methods
Population forecast data of women and men aged 50 and above in Singapore from 2017 to 2035 was used along with prevalence rates of osteoporosis to project the osteoporosis population over time. The population projections by sex and age group were used along with osteoporotic fracture incidence rates by fracture type (hip, vertebral, other), and average direct and indirect costs per case to forecast the number of fractures, the total direct health care costs, and the total indirect costs due to fractures in Singapore. Data on treatment rates and effects were used to model the health and economic impact of increasing treatment rate of osteoporosis, using different hypothetical levels.
Results
Between 2017 and 2035, the incidence of osteoporotic fractures is projected to increase from 15,267 to 24,104 (a 57.9% increase) F 10,717 to 17,225 (a 60.7% increase) and M 4550 to 6878 (a 51.2% increase). The total economic burden (including direct costs and indirect costs to society) associated with these fractures is estimated at S$183.5 million in 2017 and is forecasted to grow to S$289.6 million by 2035. However, increasing the treatment rate for osteoporosis could avert up to 29,096 fractures over the forecast period (2017–2035), generating cumulative total cost savings of up to S$330.6 million.
Conclusion
Efforts to improve the detection, diagnosis, and treatment of osteoporosis are necessary to reduce the growing clinical, economic, and societal burden of fractures in Singapore.</description><identifier>ISSN: 1862-3522</identifier><identifier>EISSN: 1862-3514</identifier><identifier>DOI: 10.1007/s11657-019-0664-4</identifier><identifier>PMID: 31773442</identifier><language>eng</language><publisher>London: Springer London</publisher><subject>Age Distribution ; Aged ; Aged, 80 and over ; Bone Density Conservation Agents - therapeutic use ; Cost of Illness ; Cost Savings - economics ; Cost Savings - statistics & numerical data ; Drug Utilization - statistics & numerical data ; Drug Utilization - trends ; Endocrinology ; Female ; Health Care Costs - statistics & numerical data ; Health Care Costs - trends ; Humans ; Incidence ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Original Article ; Orthopedics ; Osteoporosis - drug therapy ; Osteoporosis - epidemiology ; Osteoporotic Fractures - economics ; Osteoporotic Fractures - epidemiology ; Osteoporotic Fractures - prevention & control ; Prevalence ; Risk Assessment - methods ; Sex Distribution ; Singapore - epidemiology</subject><ispartof>Archives of osteoporosis, 2019-12, Vol.14 (1), p.114-114, Article 114</ispartof><rights>International Osteoporosis Foundation and National Osteoporosis Foundation 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c377t-124ca4974af52e84895197ed3917255eab9e9643f220e738b4d4d2ca86765cb43</citedby><cites>FETCH-LOGICAL-c377t-124ca4974af52e84895197ed3917255eab9e9643f220e738b4d4d2ca86765cb43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11657-019-0664-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11657-019-0664-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31773442$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chandran, Manju</creatorcontrib><creatorcontrib>Lau, Tang Ching</creatorcontrib><creatorcontrib>Gagnon-Arpin, Isabelle</creatorcontrib><creatorcontrib>Dobrescu, Alexandru</creatorcontrib><creatorcontrib>Li, Wenshan</creatorcontrib><creatorcontrib>Leung, Man Yee Mallory</creatorcontrib><creatorcontrib>Patil, Narendra</creatorcontrib><creatorcontrib>Zhao, Zhongyun</creatorcontrib><title>The health and economic burden of osteoporotic fractures in Singapore and the potential impact of increasing treatment rates through more pharmacological options</title><title>Archives of osteoporosis</title><addtitle>Arch Osteoporos</addtitle><addtitle>Arch Osteoporos</addtitle><description>Purpose
This study aims to estimate the health and economic burden of osteoporosis in Singapore from 2017 to 2035, and to quantify the impact of increasing the treatment rate of osteoporosis.
Methods
Population forecast data of women and men aged 50 and above in Singapore from 2017 to 2035 was used along with prevalence rates of osteoporosis to project the osteoporosis population over time. The population projections by sex and age group were used along with osteoporotic fracture incidence rates by fracture type (hip, vertebral, other), and average direct and indirect costs per case to forecast the number of fractures, the total direct health care costs, and the total indirect costs due to fractures in Singapore. Data on treatment rates and effects were used to model the health and economic impact of increasing treatment rate of osteoporosis, using different hypothetical levels.
Results
Between 2017 and 2035, the incidence of osteoporotic fractures is projected to increase from 15,267 to 24,104 (a 57.9% increase) F 10,717 to 17,225 (a 60.7% increase) and M 4550 to 6878 (a 51.2% increase). The total economic burden (including direct costs and indirect costs to society) associated with these fractures is estimated at S$183.5 million in 2017 and is forecasted to grow to S$289.6 million by 2035. However, increasing the treatment rate for osteoporosis could avert up to 29,096 fractures over the forecast period (2017–2035), generating cumulative total cost savings of up to S$330.6 million.
Conclusion
Efforts to improve the detection, diagnosis, and treatment of osteoporosis are necessary to reduce the growing clinical, economic, and societal burden of fractures in Singapore.</description><subject>Age Distribution</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Bone Density Conservation Agents - therapeutic use</subject><subject>Cost of Illness</subject><subject>Cost Savings - economics</subject><subject>Cost Savings - statistics & numerical data</subject><subject>Drug Utilization - statistics & numerical data</subject><subject>Drug Utilization - trends</subject><subject>Endocrinology</subject><subject>Female</subject><subject>Health Care Costs - statistics & numerical data</subject><subject>Health Care Costs - trends</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Original Article</subject><subject>Orthopedics</subject><subject>Osteoporosis - drug therapy</subject><subject>Osteoporosis - epidemiology</subject><subject>Osteoporotic Fractures - economics</subject><subject>Osteoporotic Fractures - epidemiology</subject><subject>Osteoporotic Fractures - prevention & control</subject><subject>Prevalence</subject><subject>Risk Assessment - methods</subject><subject>Sex Distribution</subject><subject>Singapore - epidemiology</subject><issn>1862-3522</issn><issn>1862-3514</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kb1u3iAUhlHVqvlpL6BLxdjFCX8GM1ZR2kaKlKHpjDA-_kxkgwt4yOXkTov7JRkzccR53kc6ehH6QskFJURdZkplqxpCdUOkFI14h05pJ1nDWyrev86MnaCznB8IkYS28iM64VQpLgQ7RU_3E-AJ7FwmbMOAwcUQF-9wv6UBAo4jjrlAXGOKpX6PybqyJcjYB_zbh4OtG_gfLdW0xgKheDtjv6yV3PM-uAQ2VxaXOpSlEjjZUh1lSnE7THjZHetk02JdnOPBu2qIa_Ex5E_ow2jnDJ-f33P058f1_dWv5vbu583V99vGcaVKQ5lwVmgl7Ngy6ESnW6oVDFxTxdoWbK9BS8FHxggo3vViEANztpNKtq4X_Bx9O3rXFP9ukItZfHYwzzZA3LJhnGqqheBdRekRdSnmnGA0a_KLTY-GErM3Y47NmNqM2Zsxu_7rs37rFxheEy9VVIAdgVxX4QDJPMQthXryG9Z_Et6cuQ</recordid><startdate>20191201</startdate><enddate>20191201</enddate><creator>Chandran, Manju</creator><creator>Lau, Tang Ching</creator><creator>Gagnon-Arpin, Isabelle</creator><creator>Dobrescu, Alexandru</creator><creator>Li, Wenshan</creator><creator>Leung, Man Yee Mallory</creator><creator>Patil, Narendra</creator><creator>Zhao, Zhongyun</creator><general>Springer London</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20191201</creationdate><title>The health and economic burden of osteoporotic fractures in Singapore and the potential impact of increasing treatment rates through more pharmacological options</title><author>Chandran, Manju ; Lau, Tang Ching ; Gagnon-Arpin, Isabelle ; Dobrescu, Alexandru ; Li, Wenshan ; Leung, Man Yee Mallory ; Patil, Narendra ; Zhao, Zhongyun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c377t-124ca4974af52e84895197ed3917255eab9e9643f220e738b4d4d2ca86765cb43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Age Distribution</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Bone Density Conservation Agents - therapeutic use</topic><topic>Cost of Illness</topic><topic>Cost Savings - economics</topic><topic>Cost Savings - statistics & numerical data</topic><topic>Drug Utilization - statistics & numerical data</topic><topic>Drug Utilization - trends</topic><topic>Endocrinology</topic><topic>Female</topic><topic>Health Care Costs - statistics & numerical data</topic><topic>Health Care Costs - trends</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Original Article</topic><topic>Orthopedics</topic><topic>Osteoporosis - drug therapy</topic><topic>Osteoporosis - epidemiology</topic><topic>Osteoporotic Fractures - economics</topic><topic>Osteoporotic Fractures - epidemiology</topic><topic>Osteoporotic Fractures - prevention & control</topic><topic>Prevalence</topic><topic>Risk Assessment - methods</topic><topic>Sex Distribution</topic><topic>Singapore - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chandran, Manju</creatorcontrib><creatorcontrib>Lau, Tang Ching</creatorcontrib><creatorcontrib>Gagnon-Arpin, Isabelle</creatorcontrib><creatorcontrib>Dobrescu, Alexandru</creatorcontrib><creatorcontrib>Li, Wenshan</creatorcontrib><creatorcontrib>Leung, Man Yee Mallory</creatorcontrib><creatorcontrib>Patil, Narendra</creatorcontrib><creatorcontrib>Zhao, Zhongyun</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of osteoporosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chandran, Manju</au><au>Lau, Tang Ching</au><au>Gagnon-Arpin, Isabelle</au><au>Dobrescu, Alexandru</au><au>Li, Wenshan</au><au>Leung, Man Yee Mallory</au><au>Patil, Narendra</au><au>Zhao, Zhongyun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The health and economic burden of osteoporotic fractures in Singapore and the potential impact of increasing treatment rates through more pharmacological options</atitle><jtitle>Archives of osteoporosis</jtitle><stitle>Arch Osteoporos</stitle><addtitle>Arch Osteoporos</addtitle><date>2019-12-01</date><risdate>2019</risdate><volume>14</volume><issue>1</issue><spage>114</spage><epage>114</epage><pages>114-114</pages><artnum>114</artnum><issn>1862-3522</issn><eissn>1862-3514</eissn><abstract>Purpose
This study aims to estimate the health and economic burden of osteoporosis in Singapore from 2017 to 2035, and to quantify the impact of increasing the treatment rate of osteoporosis.
Methods
Population forecast data of women and men aged 50 and above in Singapore from 2017 to 2035 was used along with prevalence rates of osteoporosis to project the osteoporosis population over time. The population projections by sex and age group were used along with osteoporotic fracture incidence rates by fracture type (hip, vertebral, other), and average direct and indirect costs per case to forecast the number of fractures, the total direct health care costs, and the total indirect costs due to fractures in Singapore. Data on treatment rates and effects were used to model the health and economic impact of increasing treatment rate of osteoporosis, using different hypothetical levels.
Results
Between 2017 and 2035, the incidence of osteoporotic fractures is projected to increase from 15,267 to 24,104 (a 57.9% increase) F 10,717 to 17,225 (a 60.7% increase) and M 4550 to 6878 (a 51.2% increase). The total economic burden (including direct costs and indirect costs to society) associated with these fractures is estimated at S$183.5 million in 2017 and is forecasted to grow to S$289.6 million by 2035. However, increasing the treatment rate for osteoporosis could avert up to 29,096 fractures over the forecast period (2017–2035), generating cumulative total cost savings of up to S$330.6 million.
Conclusion
Efforts to improve the detection, diagnosis, and treatment of osteoporosis are necessary to reduce the growing clinical, economic, and societal burden of fractures in Singapore.</abstract><cop>London</cop><pub>Springer London</pub><pmid>31773442</pmid><doi>10.1007/s11657-019-0664-4</doi><tpages>1</tpages></addata></record> |
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| ispartof | Archives of osteoporosis, 2019-12, Vol.14 (1), p.114-114, Article 114 |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Age Distribution Aged Aged, 80 and over Bone Density Conservation Agents - therapeutic use Cost of Illness Cost Savings - economics Cost Savings - statistics & numerical data Drug Utilization - statistics & numerical data Drug Utilization - trends Endocrinology Female Health Care Costs - statistics & numerical data Health Care Costs - trends Humans Incidence Male Medicine Medicine & Public Health Middle Aged Original Article Orthopedics Osteoporosis - drug therapy Osteoporosis - epidemiology Osteoporotic Fractures - economics Osteoporotic Fractures - epidemiology Osteoporotic Fractures - prevention & control Prevalence Risk Assessment - methods Sex Distribution Singapore - epidemiology |
| title | The health and economic burden of osteoporotic fractures in Singapore and the potential impact of increasing treatment rates through more pharmacological options |
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