Fine needle aspiration cytology of minor salivary gland tumors: A retrospective 5-year study of 42 cases in a tertiary care hospital
Background: Minor salivary gland tumors (MSGTs) are less common than major salivary glands and involve only 15-20% of all salivary gland tumors. Most of the cases originate at intra- and peri-oral region. Minor salivary gland lesion cytology has been studied rarely in India. Aims: This present study...
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| Veröffentlicht in: | Journal of cancer research and therapeutics 2019-07, Vol.15 (3), p.686-689 |
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| creator | Pal, Subrata Mondal, Sajeeb Bose, Kingshuk Pradhan, Rajashree Bandyapadhyay, Arindam Bhattacharyya, Debosmita |
| description | Background: Minor salivary gland tumors (MSGTs) are less common than major salivary glands and involve only 15-20% of all salivary gland tumors. Most of the cases originate at intra- and peri-oral region. Minor salivary gland lesion cytology has been studied rarely in India.
Aims: This present study was performed to evaluate the role of fine needle aspiration cytology (FNAC) in diagnosis of MSGTs and to explore the cases of cytohistological discrepancies in the study.
Materials and Methods: This retrospective study was conducted over a 5-year period on 42 cases of MSGTs. In all the cases, cytology was correlated with histology and cytohistological discrepancies were searched. Sensitivity, specificity, and diagnostic efficacy were calculated using histopathology as gold standard.
Results: We diagnosed 27 malignant (64.28%) and 15 benign (35.71%) MSGTs in cytological evaluation. We found two false negative and one false positive case in cytology. Sensitivity, specificity, and diagnostic accuracy of the study were 92.59%, 93.33%, and 92.85%, respectively.
Conclusion: FNAC is a minimally invasive and cost-effective procedure with high accuracy (92.85%) in the assessment of MSGTs and helps in the management of benign and malignant tumors. |
| doi_str_mv | 10.4103/0973-1482.191055 |
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Aims: This present study was performed to evaluate the role of fine needle aspiration cytology (FNAC) in diagnosis of MSGTs and to explore the cases of cytohistological discrepancies in the study.
Materials and Methods: This retrospective study was conducted over a 5-year period on 42 cases of MSGTs. In all the cases, cytology was correlated with histology and cytohistological discrepancies were searched. Sensitivity, specificity, and diagnostic efficacy were calculated using histopathology as gold standard.
Results: We diagnosed 27 malignant (64.28%) and 15 benign (35.71%) MSGTs in cytological evaluation. We found two false negative and one false positive case in cytology. Sensitivity, specificity, and diagnostic accuracy of the study were 92.59%, 93.33%, and 92.85%, respectively.
Conclusion: FNAC is a minimally invasive and cost-effective procedure with high accuracy (92.85%) in the assessment of MSGTs and helps in the management of benign and malignant tumors.</description><identifier>ISSN: 0973-1482</identifier><identifier>EISSN: 1998-4138</identifier><identifier>DOI: 10.4103/0973-1482.191055</identifier><identifier>PMID: 31169241</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Adolescent ; Adult ; Age ; Aged ; Biopsy, Fine-Needle ; Care and treatment ; Cellular biology ; Child ; Cytodiagnosis - methods ; Female ; Histopathology ; Humans ; Male ; Middle Aged ; Needle biopsy ; Neoplasm Grading ; Neoplasm Staging ; Oral cancer ; Reproducibility of Results ; Retrospective Studies ; Salivary Gland Neoplasms - diagnosis ; Salivary Gland Neoplasms - pathology ; Salivary gland tumors ; Salivary Glands, Minor - pathology ; Sensitivity and Specificity ; Studies ; Tertiary Care Centers ; Tumors ; Young Adult</subject><ispartof>Journal of cancer research and therapeutics, 2019-07, Vol.15 (3), p.686-689</ispartof><rights>COPYRIGHT 2019 Medknow Publications and Media Pvt. Ltd.</rights><rights>2019. This work is published under https://creativecommons.org/licenses/by-nc-sa/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c456i-10208554a5be6dea11821ac874375c82056ed8f749fb5b4a3da3d380fb72afec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27458,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31169241$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pal, Subrata</creatorcontrib><creatorcontrib>Mondal, Sajeeb</creatorcontrib><creatorcontrib>Bose, Kingshuk</creatorcontrib><creatorcontrib>Pradhan, Rajashree</creatorcontrib><creatorcontrib>Bandyapadhyay, Arindam</creatorcontrib><creatorcontrib>Bhattacharyya, Debosmita</creatorcontrib><title>Fine needle aspiration cytology of minor salivary gland tumors: A retrospective 5-year study of 42 cases in a tertiary care hospital</title><title>Journal of cancer research and therapeutics</title><addtitle>J Cancer Res Ther</addtitle><description>Background: Minor salivary gland tumors (MSGTs) are less common than major salivary glands and involve only 15-20% of all salivary gland tumors. Most of the cases originate at intra- and peri-oral region. Minor salivary gland lesion cytology has been studied rarely in India.
Aims: This present study was performed to evaluate the role of fine needle aspiration cytology (FNAC) in diagnosis of MSGTs and to explore the cases of cytohistological discrepancies in the study.
Materials and Methods: This retrospective study was conducted over a 5-year period on 42 cases of MSGTs. In all the cases, cytology was correlated with histology and cytohistological discrepancies were searched. Sensitivity, specificity, and diagnostic efficacy were calculated using histopathology as gold standard.
Results: We diagnosed 27 malignant (64.28%) and 15 benign (35.71%) MSGTs in cytological evaluation. We found two false negative and one false positive case in cytology. Sensitivity, specificity, and diagnostic accuracy of the study were 92.59%, 93.33%, and 92.85%, respectively.
Conclusion: FNAC is a minimally invasive and cost-effective procedure with high accuracy (92.85%) in the assessment of MSGTs and helps in the management of benign and malignant tumors.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Aged</subject><subject>Biopsy, Fine-Needle</subject><subject>Care and treatment</subject><subject>Cellular biology</subject><subject>Child</subject><subject>Cytodiagnosis - methods</subject><subject>Female</subject><subject>Histopathology</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Needle biopsy</subject><subject>Neoplasm Grading</subject><subject>Neoplasm Staging</subject><subject>Oral cancer</subject><subject>Reproducibility of Results</subject><subject>Retrospective Studies</subject><subject>Salivary Gland Neoplasms - diagnosis</subject><subject>Salivary Gland Neoplasms - pathology</subject><subject>Salivary gland tumors</subject><subject>Salivary Glands, Minor - pathology</subject><subject>Sensitivity and Specificity</subject><subject>Studies</subject><subject>Tertiary Care Centers</subject><subject>Tumors</subject><subject>Young Adult</subject><issn>0973-1482</issn><issn>1998-4138</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptks9v0zAYhiMEYt3gzglZ4sIlxT8Th1s1bYA0wQXOlut8Kd4cu9jOqt75w3HWbTBUxVKk-Hlf-YufqnpD8JITzD7grmU14ZIuSUewEM-qBek6WXPC5PNq8bh9Up2mdI2xaCmVL6sTRkjTUU4W1e9L6wF5gN4B0mlro842eGT2Obiw2aMwoNH6EFHSzt7quEcbp32P8jSGmD6iFYqQY0hbMNneAhL1HnSh89TfhTlFRidIyHqkUYaY7VxidAT0s8Rs1u5V9WLQLsHr-_dZ9ePy4vv55_rq26cv56ur2nDR2JpgiqUQXIs1ND1oQiQl2siWs1YYSbFooJdDy7thLdZcs74sJvGwbqkewLCz6v2hdxvDrwlSVqNNBlwZCMKUFGVkLuNCFvTdf-h1mKIvp1OUsgZ3Hab8L7XRDpT1Q8hRm7lUrYRsO8EZbgtVH6E24CFqFzwMtnx-wi-P8OXpYbTmaAAfAqZcRIowqG20Y_nNimA1i6JmE9RsgjqIUiJv7-eb1iP0j4EHMwrw9QDsgiu3lm7ctIOoCnvjw-5Jcf1PsWpko2an1MEp9eAU-wMEptDV</recordid><startdate>20190701</startdate><enddate>20190701</enddate><creator>Pal, Subrata</creator><creator>Mondal, Sajeeb</creator><creator>Bose, Kingshuk</creator><creator>Pradhan, Rajashree</creator><creator>Bandyapadhyay, Arindam</creator><creator>Bhattacharyya, Debosmita</creator><general>Wolters Kluwer India Pvt. 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Bandyapadhyay, Arindam ; Bhattacharyya, Debosmita</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c456i-10208554a5be6dea11821ac874375c82056ed8f749fb5b4a3da3d380fb72afec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Aged</topic><topic>Biopsy, Fine-Needle</topic><topic>Care and treatment</topic><topic>Cellular biology</topic><topic>Child</topic><topic>Cytodiagnosis - methods</topic><topic>Female</topic><topic>Histopathology</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Needle biopsy</topic><topic>Neoplasm Grading</topic><topic>Neoplasm Staging</topic><topic>Oral cancer</topic><topic>Reproducibility of Results</topic><topic>Retrospective Studies</topic><topic>Salivary Gland Neoplasms - diagnosis</topic><topic>Salivary Gland Neoplasms - pathology</topic><topic>Salivary gland tumors</topic><topic>Salivary Glands, Minor - pathology</topic><topic>Sensitivity and Specificity</topic><topic>Studies</topic><topic>Tertiary Care Centers</topic><topic>Tumors</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pal, Subrata</creatorcontrib><creatorcontrib>Mondal, Sajeeb</creatorcontrib><creatorcontrib>Bose, Kingshuk</creatorcontrib><creatorcontrib>Pradhan, Rajashree</creatorcontrib><creatorcontrib>Bandyapadhyay, Arindam</creatorcontrib><creatorcontrib>Bhattacharyya, Debosmita</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cancer research and therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pal, Subrata</au><au>Mondal, Sajeeb</au><au>Bose, Kingshuk</au><au>Pradhan, Rajashree</au><au>Bandyapadhyay, Arindam</au><au>Bhattacharyya, Debosmita</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fine needle aspiration cytology of minor salivary gland tumors: A retrospective 5-year study of 42 cases in a tertiary care hospital</atitle><jtitle>Journal of cancer research and therapeutics</jtitle><addtitle>J Cancer Res Ther</addtitle><date>2019-07-01</date><risdate>2019</risdate><volume>15</volume><issue>3</issue><spage>686</spage><epage>689</epage><pages>686-689</pages><issn>0973-1482</issn><eissn>1998-4138</eissn><abstract>Background: Minor salivary gland tumors (MSGTs) are less common than major salivary glands and involve only 15-20% of all salivary gland tumors. Most of the cases originate at intra- and peri-oral region. Minor salivary gland lesion cytology has been studied rarely in India.
Aims: This present study was performed to evaluate the role of fine needle aspiration cytology (FNAC) in diagnosis of MSGTs and to explore the cases of cytohistological discrepancies in the study.
Materials and Methods: This retrospective study was conducted over a 5-year period on 42 cases of MSGTs. In all the cases, cytology was correlated with histology and cytohistological discrepancies were searched. Sensitivity, specificity, and diagnostic efficacy were calculated using histopathology as gold standard.
Results: We diagnosed 27 malignant (64.28%) and 15 benign (35.71%) MSGTs in cytological evaluation. We found two false negative and one false positive case in cytology. Sensitivity, specificity, and diagnostic accuracy of the study were 92.59%, 93.33%, and 92.85%, respectively.
Conclusion: FNAC is a minimally invasive and cost-effective procedure with high accuracy (92.85%) in the assessment of MSGTs and helps in the management of benign and malignant tumors.</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>31169241</pmid><doi>10.4103/0973-1482.191055</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Adult Age Aged Biopsy, Fine-Needle Care and treatment Cellular biology Child Cytodiagnosis - methods Female Histopathology Humans Male Middle Aged Needle biopsy Neoplasm Grading Neoplasm Staging Oral cancer Reproducibility of Results Retrospective Studies Salivary Gland Neoplasms - diagnosis Salivary Gland Neoplasms - pathology Salivary gland tumors Salivary Glands, Minor - pathology Sensitivity and Specificity Studies Tertiary Care Centers Tumors Young Adult |
| title | Fine needle aspiration cytology of minor salivary gland tumors: A retrospective 5-year study of 42 cases in a tertiary care hospital |
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