Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2low ATL and various cancer cells

N-myc downstream-regulated gene 2 (NDRG2) as a tumor suppressor is frequently downregulated in human T-lymphotropic retrovirus (HTLV-1)-infected adult T-cell leukemia (ATL) and variety of cancers, and negatively regulates PI3K signaling pathways through dephosphorylation of PTEN with protein phospha...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular cell research 2020-02, Vol.1867 (2), p.118615-118615, Article 118615
Hauptverfasser:	Ichikawa, Tomonaga, Shanab, Obeid, Nakahata, Shingo, Shimosaki, Shunsuke, Manachai, Nawin, Ono, Masaya, Iha, Hidekatsu, Shimoda, Kazuya, Morishita, Kazuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	HSP90 NDRG2 PP2A PRMT5
Online-Zugang:	Volltext
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