QRFP administration into the medial hypothalamic nuclei improves memory in rats

•QRFP was microinjected into the medial hypothalamic area of male Wistar rats.•400 ng QRFP improved consolidation of short-term memory in Morris water maze.•The effective dose of QRFP did not affect nor general locomotion activity, neither anxiety level.•Pretreatment with receptor antagonist BIBP322...

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Veröffentlicht in:	Brain research 2020-01, Vol.1727, p.146563-146563, Article 146563
Hauptverfasser:	Zagorácz, Olga, Ollmann, Tamás, Péczely, László, László, Kristóf, Kovács, Anita, Berta, Beáta, Kállai, Veronika, Kertes, Erika, Lénárd, László
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antagonist BIBP3226 Behavior, Animal - drug effects Behavior, Animal - physiology Elevated plus maze Hypothalamus, Middle - drug effects Hypothalamus, Middle - physiology Intercellular Signaling Peptides and Proteins - administration & dosage Intercellular Signaling Peptides and Proteins - physiology Male Maze Learning - drug effects Maze Learning - physiology Medial hypothalamus Memory - drug effects Memory - physiology Morris water maze QRFP Rats, Wistar Spatial memory
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