Updates on immunologic correlates of vaccine-induced protection
Correlates of protection (CoPs) are increasingly important in the development and licensure of vaccines. Although the study of CoPs was initially directed at identifying a single immune function that could explain vaccine efficacy, it has become increasingly clear that there are often multiple funct...
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| Veröffentlicht in: | Vaccine 2020-02, Vol.38 (9), p.2250-2257 |
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| container_title | Vaccine |
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| creator | Plotkin, Stanley A. |
| description | Correlates of protection (CoPs) are increasingly important in the development and licensure of vaccines. Although the study of CoPs was initially directed at identifying a single immune function that could explain vaccine efficacy, it has become increasingly clear that there are often multiple functions responsible for efficacy. This review is meant to supplement prior articles on the subject, illustrating both simple and complex CoPs. |
| doi_str_mv | 10.1016/j.vaccine.2019.10.046 |
| format | Article |
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| identifier | ISSN: 0264-410X |
| ispartof | Vaccine, 2020-02, Vol.38 (9), p.2250-2257 |
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| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present); ProQuest Central UK/Ireland |
| subjects | Antibodies Antigens Cell mediated immunity Cholera Communicable Disease Control Communicable Diseases - immunology Correlates Cytomegalovirus Cytotoxicity E coli Ebola virus Epidemics Glycoproteins Humans Immune response Immune system Immunoglobulins Infections Influenza Lymphocytes Proteins Stem cells Vaccine efficacy Vaccines Vaccines - immunology |
| title | Updates on immunologic correlates of vaccine-induced protection |
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