Predictors for recovery of macular function after surgery for primary macula-off rhegmatogenous retinal detachment
Purpose To determine predictors of best-corrected postoperative visual acuity (VA) in patients who underwent surgical intervention for macula-off rhegmatogenous retinal detachment. Materials and methods Primary macula-off retinal detachments from the University of Colorado Primary Rhegmatogenous Ret...
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| Veröffentlicht in: | International ophthalmology 2020-03, Vol.40 (3), p.609-616 |
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| creator | Geiger, Matthew Smith, Jesse M. Lynch, Anne Patnaik, Jennifer L. Oliver, Scott C. N. Dixon, James A. Mandava, Naresh Palestine, Alan G. |
| description | Purpose
To determine predictors of best-corrected postoperative visual acuity (VA) in patients who underwent surgical intervention for macula-off rhegmatogenous retinal detachment.
Materials and methods
Primary macula-off retinal detachments from the University of Colorado Primary Rhegmatogenous Retinal Detachment Database (2012–2017) were reviewed. The primary outcome measure was a postoperative VA of 20/40 or better at least 6 months after surgery. Patient demographics, medical history, duration of central vision loss before surgery, examination findings, operative technique, and postoperative findings were analyzed as possible predictors of postoperative visual recovery to 20/40 or better. Chi-square or Fisher’s exact test was used to compare categorical variables, and Wilcoxon rank sum test was used for continuous variables. A multivariable logistic regression analysis was used to determine the adjusted odds ratios and 95% confidence intervals for variables that were significant in the univariable analyses. Statistical significance was set at
p
|
| doi_str_mv | 10.1007/s10792-019-01219-0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2318727032</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2376507815</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-5c49000c9540f30435df1834efda1b09363763d2709f00d7dbc56e3745f5eea43</originalsourceid><addsrcrecordid>eNp9kUtLxDAUhYMoOj7-gAsJuHFTvWmapl2K-AJBF7oOmfRmrLSNJqngvze1o4ILF3lAvnNykkPIIYNTBiDPAgNZ5xmwOo18mjfIggnJs7zksEkWwEqRCQlsh-yG8AIAtazLbbLDmSyrivEF8Q8em9ZE5wO1zlOPxr2j_6DO0l6bsdOe2nEwsXUD1Taip2H0q4mY8Fff9jrtZzRz1lL_jKteR7fCwY0hGcZ20B1tMGrz3OMQ98mW1V3Ag_W6R56uLh8vbrK7--vbi_O7zHApYiZMUafEphYFWA4FF41lFS_QNpotoeYllyVvcgm1BWhkszSiRC4LYQWiLvgeOZl9X717GzFE1bfBYNfpAVMylXNWySTneUKP_6AvbvQp9kTJUoCsmEhUPlPGuxA8WrV-vmKgpkbU3IhKjaivRhQk0dHaelz22PxIvitIAJ-BkI6G9LO_d_9j-wkLMZeI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2376507815</pqid></control><display><type>article</type><title>Predictors for recovery of macular function after surgery for primary macula-off rhegmatogenous retinal detachment</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Geiger, Matthew ; Smith, Jesse M. ; Lynch, Anne ; Patnaik, Jennifer L. ; Oliver, Scott C. N. ; Dixon, James A. ; Mandava, Naresh ; Palestine, Alan G.</creator><creatorcontrib>Geiger, Matthew ; Smith, Jesse M. ; Lynch, Anne ; Patnaik, Jennifer L. ; Oliver, Scott C. N. ; Dixon, James A. ; Mandava, Naresh ; Palestine, Alan G. ; University of Colorado Retina Research Group ; The University of Colorado Retina Research Group</creatorcontrib><description>Purpose
To determine predictors of best-corrected postoperative visual acuity (VA) in patients who underwent surgical intervention for macula-off rhegmatogenous retinal detachment.
Materials and methods
Primary macula-off retinal detachments from the University of Colorado Primary Rhegmatogenous Retinal Detachment Database (2012–2017) were reviewed. The primary outcome measure was a postoperative VA of 20/40 or better at least 6 months after surgery. Patient demographics, medical history, duration of central vision loss before surgery, examination findings, operative technique, and postoperative findings were analyzed as possible predictors of postoperative visual recovery to 20/40 or better. Chi-square or Fisher’s exact test was used to compare categorical variables, and Wilcoxon rank sum test was used for continuous variables. A multivariable logistic regression analysis was used to determine the adjusted odds ratios and 95% confidence intervals for variables that were significant in the univariable analyses. Statistical significance was set at
p
< 0.05.
Results
One hundred thirty-one patients met inclusion criteria. Eighty-one (61.8%) patients achieved a postoperative VA of 20/40 or better 6 or more months after surgery. Patients with a single retinal break were more likely than patients with more than one break to reach a postoperative VA of 20/40 or better (76.9% vs. 55.4%,
p
= 0.021). Patients with a better preoperative logMAR VA had better postoperative VA (
p
= 0.021). Duration of central vision loss prior to surgical repair was not related to final postoperative VA in this particular study.
Conclusion
Postoperative recovery of visual acuity to 20/40 or better was significantly more common in patients with a single retinal break as well as in patients with better preoperative visual acuity. Duration of central vision loss prior to surgical repair was not significantly associated with postoperative VA.</description><identifier>ISSN: 0165-5701</identifier><identifier>EISSN: 1573-2630</identifier><identifier>DOI: 10.1007/s10792-019-01219-0</identifier><identifier>PMID: 31768813</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Acuity ; Adult ; Aged ; Aged, 80 and over ; Confidence intervals ; Continuity (mathematics) ; Demography ; Female ; Follow-Up Studies ; Humans ; Macula Lutea - diagnostic imaging ; Macula Lutea - physiopathology ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Ophthalmology ; Original Paper ; Patients ; Postoperative Period ; Recovery ; Recovery of Function ; Regression analysis ; Retina ; Retinal Detachment - diagnosis ; Retinal Detachment - physiopathology ; Retinal Detachment - surgery ; Retrospective Studies ; Scleral Buckling - methods ; Statistical analysis ; Surgery ; Vision ; Visual acuity ; Visual Acuity - physiology ; Vitrectomy - methods ; Young Adult</subject><ispartof>International ophthalmology, 2020-03, Vol.40 (3), p.609-616</ispartof><rights>Springer Nature B.V. 2019</rights><rights>International Ophthalmology is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-5c49000c9540f30435df1834efda1b09363763d2709f00d7dbc56e3745f5eea43</citedby><cites>FETCH-LOGICAL-c375t-5c49000c9540f30435df1834efda1b09363763d2709f00d7dbc56e3745f5eea43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10792-019-01219-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10792-019-01219-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31768813$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Geiger, Matthew</creatorcontrib><creatorcontrib>Smith, Jesse M.</creatorcontrib><creatorcontrib>Lynch, Anne</creatorcontrib><creatorcontrib>Patnaik, Jennifer L.</creatorcontrib><creatorcontrib>Oliver, Scott C. N.</creatorcontrib><creatorcontrib>Dixon, James A.</creatorcontrib><creatorcontrib>Mandava, Naresh</creatorcontrib><creatorcontrib>Palestine, Alan G.</creatorcontrib><creatorcontrib>University of Colorado Retina Research Group</creatorcontrib><creatorcontrib>The University of Colorado Retina Research Group</creatorcontrib><title>Predictors for recovery of macular function after surgery for primary macula-off rhegmatogenous retinal detachment</title><title>International ophthalmology</title><addtitle>Int Ophthalmol</addtitle><addtitle>Int Ophthalmol</addtitle><description>Purpose
To determine predictors of best-corrected postoperative visual acuity (VA) in patients who underwent surgical intervention for macula-off rhegmatogenous retinal detachment.
Materials and methods
Primary macula-off retinal detachments from the University of Colorado Primary Rhegmatogenous Retinal Detachment Database (2012–2017) were reviewed. The primary outcome measure was a postoperative VA of 20/40 or better at least 6 months after surgery. Patient demographics, medical history, duration of central vision loss before surgery, examination findings, operative technique, and postoperative findings were analyzed as possible predictors of postoperative visual recovery to 20/40 or better. Chi-square or Fisher’s exact test was used to compare categorical variables, and Wilcoxon rank sum test was used for continuous variables. A multivariable logistic regression analysis was used to determine the adjusted odds ratios and 95% confidence intervals for variables that were significant in the univariable analyses. Statistical significance was set at
p
< 0.05.
Results
One hundred thirty-one patients met inclusion criteria. Eighty-one (61.8%) patients achieved a postoperative VA of 20/40 or better 6 or more months after surgery. Patients with a single retinal break were more likely than patients with more than one break to reach a postoperative VA of 20/40 or better (76.9% vs. 55.4%,
p
= 0.021). Patients with a better preoperative logMAR VA had better postoperative VA (
p
= 0.021). Duration of central vision loss prior to surgical repair was not related to final postoperative VA in this particular study.
Conclusion
Postoperative recovery of visual acuity to 20/40 or better was significantly more common in patients with a single retinal break as well as in patients with better preoperative visual acuity. Duration of central vision loss prior to surgical repair was not significantly associated with postoperative VA.</description><subject>Acuity</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Confidence intervals</subject><subject>Continuity (mathematics)</subject><subject>Demography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Macula Lutea - diagnostic imaging</subject><subject>Macula Lutea - physiopathology</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Ophthalmology</subject><subject>Original Paper</subject><subject>Patients</subject><subject>Postoperative Period</subject><subject>Recovery</subject><subject>Recovery of Function</subject><subject>Regression analysis</subject><subject>Retina</subject><subject>Retinal Detachment - diagnosis</subject><subject>Retinal Detachment - physiopathology</subject><subject>Retinal Detachment - surgery</subject><subject>Retrospective Studies</subject><subject>Scleral Buckling - methods</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Vision</subject><subject>Visual acuity</subject><subject>Visual Acuity - physiology</subject><subject>Vitrectomy - methods</subject><subject>Young Adult</subject><issn>0165-5701</issn><issn>1573-2630</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kUtLxDAUhYMoOj7-gAsJuHFTvWmapl2K-AJBF7oOmfRmrLSNJqngvze1o4ILF3lAvnNykkPIIYNTBiDPAgNZ5xmwOo18mjfIggnJs7zksEkWwEqRCQlsh-yG8AIAtazLbbLDmSyrivEF8Q8em9ZE5wO1zlOPxr2j_6DO0l6bsdOe2nEwsXUD1Taip2H0q4mY8Fff9jrtZzRz1lL_jKteR7fCwY0hGcZ20B1tMGrz3OMQ98mW1V3Ag_W6R56uLh8vbrK7--vbi_O7zHApYiZMUafEphYFWA4FF41lFS_QNpotoeYllyVvcgm1BWhkszSiRC4LYQWiLvgeOZl9X717GzFE1bfBYNfpAVMylXNWySTneUKP_6AvbvQp9kTJUoCsmEhUPlPGuxA8WrV-vmKgpkbU3IhKjaivRhQk0dHaelz22PxIvitIAJ-BkI6G9LO_d_9j-wkLMZeI</recordid><startdate>20200301</startdate><enddate>20200301</enddate><creator>Geiger, Matthew</creator><creator>Smith, Jesse M.</creator><creator>Lynch, Anne</creator><creator>Patnaik, Jennifer L.</creator><creator>Oliver, Scott C. N.</creator><creator>Dixon, James A.</creator><creator>Mandava, Naresh</creator><creator>Palestine, Alan G.</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20200301</creationdate><title>Predictors for recovery of macular function after surgery for primary macula-off rhegmatogenous retinal detachment</title><author>Geiger, Matthew ; Smith, Jesse M. ; Lynch, Anne ; Patnaik, Jennifer L. ; Oliver, Scott C. N. ; Dixon, James A. ; Mandava, Naresh ; Palestine, Alan G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-5c49000c9540f30435df1834efda1b09363763d2709f00d7dbc56e3745f5eea43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acuity</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Confidence intervals</topic><topic>Continuity (mathematics)</topic><topic>Demography</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Macula Lutea - diagnostic imaging</topic><topic>Macula Lutea - physiopathology</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Ophthalmology</topic><topic>Original Paper</topic><topic>Patients</topic><topic>Postoperative Period</topic><topic>Recovery</topic><topic>Recovery of Function</topic><topic>Regression analysis</topic><topic>Retina</topic><topic>Retinal Detachment - diagnosis</topic><topic>Retinal Detachment - physiopathology</topic><topic>Retinal Detachment - surgery</topic><topic>Retrospective Studies</topic><topic>Scleral Buckling - methods</topic><topic>Statistical analysis</topic><topic>Surgery</topic><topic>Vision</topic><topic>Visual acuity</topic><topic>Visual Acuity - physiology</topic><topic>Vitrectomy - methods</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Geiger, Matthew</creatorcontrib><creatorcontrib>Smith, Jesse M.</creatorcontrib><creatorcontrib>Lynch, Anne</creatorcontrib><creatorcontrib>Patnaik, Jennifer L.</creatorcontrib><creatorcontrib>Oliver, Scott C. N.</creatorcontrib><creatorcontrib>Dixon, James A.</creatorcontrib><creatorcontrib>Mandava, Naresh</creatorcontrib><creatorcontrib>Palestine, Alan G.</creatorcontrib><creatorcontrib>University of Colorado Retina Research Group</creatorcontrib><creatorcontrib>The University of Colorado Retina Research Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>International ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Geiger, Matthew</au><au>Smith, Jesse M.</au><au>Lynch, Anne</au><au>Patnaik, Jennifer L.</au><au>Oliver, Scott C. N.</au><au>Dixon, James A.</au><au>Mandava, Naresh</au><au>Palestine, Alan G.</au><aucorp>University of Colorado Retina Research Group</aucorp><aucorp>The University of Colorado Retina Research Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictors for recovery of macular function after surgery for primary macula-off rhegmatogenous retinal detachment</atitle><jtitle>International ophthalmology</jtitle><stitle>Int Ophthalmol</stitle><addtitle>Int Ophthalmol</addtitle><date>2020-03-01</date><risdate>2020</risdate><volume>40</volume><issue>3</issue><spage>609</spage><epage>616</epage><pages>609-616</pages><issn>0165-5701</issn><eissn>1573-2630</eissn><abstract>Purpose
To determine predictors of best-corrected postoperative visual acuity (VA) in patients who underwent surgical intervention for macula-off rhegmatogenous retinal detachment.
Materials and methods
Primary macula-off retinal detachments from the University of Colorado Primary Rhegmatogenous Retinal Detachment Database (2012–2017) were reviewed. The primary outcome measure was a postoperative VA of 20/40 or better at least 6 months after surgery. Patient demographics, medical history, duration of central vision loss before surgery, examination findings, operative technique, and postoperative findings were analyzed as possible predictors of postoperative visual recovery to 20/40 or better. Chi-square or Fisher’s exact test was used to compare categorical variables, and Wilcoxon rank sum test was used for continuous variables. A multivariable logistic regression analysis was used to determine the adjusted odds ratios and 95% confidence intervals for variables that were significant in the univariable analyses. Statistical significance was set at
p
< 0.05.
Results
One hundred thirty-one patients met inclusion criteria. Eighty-one (61.8%) patients achieved a postoperative VA of 20/40 or better 6 or more months after surgery. Patients with a single retinal break were more likely than patients with more than one break to reach a postoperative VA of 20/40 or better (76.9% vs. 55.4%,
p
= 0.021). Patients with a better preoperative logMAR VA had better postoperative VA (
p
= 0.021). Duration of central vision loss prior to surgical repair was not related to final postoperative VA in this particular study.
Conclusion
Postoperative recovery of visual acuity to 20/40 or better was significantly more common in patients with a single retinal break as well as in patients with better preoperative visual acuity. Duration of central vision loss prior to surgical repair was not significantly associated with postoperative VA.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>31768813</pmid><doi>10.1007/s10792-019-01219-0</doi><tpages>8</tpages></addata></record> |
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| ispartof | International ophthalmology, 2020-03, Vol.40 (3), p.609-616 |
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| subjects | Acuity Adult Aged Aged, 80 and over Confidence intervals Continuity (mathematics) Demography Female Follow-Up Studies Humans Macula Lutea - diagnostic imaging Macula Lutea - physiopathology Male Medicine Medicine & Public Health Middle Aged Ophthalmology Original Paper Patients Postoperative Period Recovery Recovery of Function Regression analysis Retina Retinal Detachment - diagnosis Retinal Detachment - physiopathology Retinal Detachment - surgery Retrospective Studies Scleral Buckling - methods Statistical analysis Surgery Vision Visual acuity Visual Acuity - physiology Vitrectomy - methods Young Adult |
| title | Predictors for recovery of macular function after surgery for primary macula-off rhegmatogenous retinal detachment |
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