The intestinal regionalization of acute norovirus infection is regulated by the microbiota via bile acid-mediated priming of type III interferon

Evidence has accumulated to demonstrate that the intestinal microbiota enhances mammalian enteric virus infections 1 . For example, we and others previously reported that commensal bacteria stimulate acute and persistent murine norovirus infections 2 – 4 . However, in apparent contradiction of these...

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Veröffentlicht in:Nature microbiology 2020-01, Vol.5 (1), p.84-92
Hauptverfasser: Grau, Katrina R., Zhu, Shu, Peterson, Stefan T., Helm, Emily W., Philip, Drake, Phillips, Matthew, Hernandez, Abel, Turula, Holly, Frasse, Philip, Graziano, Vincent R., Wilen, Craig B., Wobus, Christiane E., Baldridge, Megan T., Karst, Stephanie M.
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