Application of Nitroimidazole–Carbobane-Modified Phenylalanine Derivatives as Dual-Target Boron Carriers in Boron Neutron Capture Therapy

Boron neutron capture therapy (BNCT) has received extensive attention as noninvasive cell-level oncotherapy for treating solid cancer tumors. However, boron-containing drugs such as l-boronophenylalanine (BPA) and sodium borocaptate have low boron content and/or poor tumor-targeting ability, limitin...

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Veröffentlicht in:	Molecular pharmaceutics 2020-01, Vol.17 (1), p.202-211
Hauptverfasser:	Li, Ruixi, Zhang, Juanjuan, Guo, Jingxuan, Xu, Yue, Duan, Kunyuan, Zheng, Jinrong, Wan, Hao, Yuan, Zhenwei, Chen, Haiyan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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