Transcription factors NFIA and NFIB induce cellular differentiation in high-grade astrocytoma

Introduction Malignant astrocytomas are composed of heterogeneous cell populations. Compared to grade IV glioblastoma, low-grade astrocytomas have more differentiated cells and are associated with a better prognosis. Therefore, inducing cellular differentiation to alter the behaviour of high-grade a...

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Veröffentlicht in:	Journal of neuro-oncology 2020, Vol.146 (1), p.41-53
Hauptverfasser:	Chen, Kok-Siong, Bridges, Caitlin R., Lynton, Zorana, Lim, Jonathan W. C., Stringer, Brett W., Rajagopal, Revathi, Wong, Kum-Thong, Ganesan, Dharmendra, Ariffin, Hany, Day, Bryan W., Richards, Linda J., Bunt, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Astrocytoma Cell differentiation Electroporation Gene expression Glioblastoma Immunofluorescence Laboratory Investigation Medicine Medicine & Public Health Neurology Nuclear factor I Oncology Transcription factors Tumors Xenografts
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