CD81+ Exosomes Play a Pivotal Role in the Establishment of Hepatitis C Persistent Infection and Contribute Toward the Progression of Hepatocellular Carcinoma

CD81 serves as an immune modulator, playing its role in tumor growth and metastasis of hepatitis C virus (HCV)-mediated hepatocellular carcinoma (HCC). CD81 serves as a coreceptor of viral entry and is found to be enriched in exosomes. HCV E2 protein when associated with CD81 may be responsible for...

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Veröffentlicht in:Viral immunology 2019-12, Vol.32 (10), p.453-462
Hauptverfasser: Ashraf Malik, Maliha, Ishtiyaq Ali Mirza, Javeria, Umar, Muhammad, Manzoor, Sobia
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Sprache:eng
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