Silence of lncRNA ANRIL represses cell growth and promotes apoptosis in retinoblastoma cells through regulating miR-99a and c-Myc

Retinoblastoma is a rare cancer of the immature retina. This study designed to see the function of the lncRNA ANRIL in retinoblastoma Y79 cells. ANRIL, miR-99a and c-Myc expression in Y79 cells was altered by transfection and then trypan blue, transwell assay and flow cytometry were carried out to e...

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Veröffentlicht in:	Artificial cells, nanomedicine, and biotechnology nanomedicine, and biotechnology, 2019-12, Vol.47 (1), p.2265-2273
Hauptverfasser:	Wang, Xiaomin, Zhang, Xinxia, Han, Yutong, Wang, Qiuli, Ren, Yanfan, Wang, Baojun, Hu, Junxi
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - genetics Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Gene Silencing Humans MicroRNAs - genetics Neoplasm Invasiveness Proto-Oncogene Proteins c-myc - genetics Retinoblastoma - pathology RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism
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