The relevance of pathophysiological alterations in redox signaling of 4-hydroxynonenal for pharmacological therapies of major stress-associated diseases

Modern analytical methods combined with the modern concepts of redox signaling revealed 4-hydroxy-2-nonenal (4-HNE) as particular growth regulating factor involved in redox signaling under physiological and pathophysiological circumstances. In this review current knowledge of the relevance of 4-HNE...

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Veröffentlicht in:	Free radical biology & medicine 2020-09, Vol.157, p.128-153
Hauptverfasser:	Jaganjac, Morana, Milkovic, Lidija, Gegotek, Agnieszka, Cindric, Marina, Zarkovic, Kamelija, Skrzydlewska, Elzbieta, Zarkovic, Neven
Format:	Artikel
Sprache:	eng
Schlagworte:	4-hydroxynonenal Alzheimer's disease Anti-cancer therapy Atherosclerosis Cancer Cardiovascular diseases Diabetes mellitus Growth control Inflammation Lipid peroxidation Metabolic syndrome Neurodegeneration Obesity Oxidative stress Parkinson's disease Psoriasis Redox signaling
Online-Zugang:	Volltext
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