Effects of Pioglitazone on Glucose-Dependent Insulinotropic Polypeptide-Mediated Insulin Secretion and Adipocyte Receptor Expression in Patients With Type 2 Diabetes

Incretin hormone dysregulation contributes to reduced insulin secretion and hyperglycemia in patients with type 2 diabetes mellitus (T2DM). Resistance to glucose-dependent insulinotropic polypeptide (GIP) action may occur through desensitization or downregulation of β-cell GIP receptors (GIP-R). Stu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2020-02, Vol.69 (2), p.146-157
Hauptverfasser:	Tharp, William G, Gupta, Dhananjay, Sideleva, Olga, Deacon, Carolyn F, Holst, Jens J, Elahi, Dariush, Pratley, Richard E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Agonists Beta cells Cell lines Diabetes Diabetes mellitus (non-insulin dependent) Gene expression GIP protein Hyperglycemia Insulin Insulin secretion Pioglitazone Polypeptides Regulatory sequences Secretion Troglitazone
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!