Monitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environment
The occurrence of anti-inflammatory and analgesic pharmaceuticals (AIAPs) in the effluents of 16 hospitals, influent and effluent of wastewater treatment plant (WWTP), the contribution and mass load of each hospital to WWTP influent, and the removal efficiencies in WWTP were investigated. Environmen...
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| Veröffentlicht in: | Environmental science and pollution research international 2019-12, Vol.26 (36), p.36887-36902 |
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| creator | Aydin, Senar Aydin, Mehmet Emin Ulvi, Arzu |
| description | The occurrence of anti-inflammatory and analgesic pharmaceuticals (AIAPs) in the effluents of 16 hospitals, influent and effluent of wastewater treatment plant (WWTP), the contribution and mass load of each hospital to WWTP influent, and the removal efficiencies in WWTP were investigated. Environmental risk was also evaluated by toxicity tests using organisms from three different trophic levels. Acetaminophen had the highest concentration in summer and winter samples, followed by ketoprofen, ibuprofen, and naproxen. The total daily load of AIAPs detected in influent of WWTP was 1677 mg/day/1000 inhabitants in summer and 5074 mg/day/1000 inhabitants in winter. The contribution of 16 hospitals to the total AIAP load in influent of WWTP was 11.30% in summer and 7.09% in winter. The highest mass loads were calculated as 203 mg/bed.day in general hospital in summer and 300 mg/bed.day in pediatric hospital in winter. The removal efficiencies of AIAPs in WWTP ranged between 13% and 100% in summer and 0.88% and 99% in winter. WWTP is not sufficient to remove all the AIAPs. Diclofenac (in summer), mefenamic acid, indomethacin, and phenylbutazone exhibited poor removal below 50%. The effluents of the WWTP exhibited a low risk for fish and
Daphnia magna
and an insignificant risk for algae. |
| doi_str_mv | 10.1007/s11356-019-06821-4 |
| format | Article |
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Daphnia magna
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Daphnia magna
and an insignificant risk for algae.</description><subject>Acetaminophen</subject><subject>Algae</subject><subject>Analgesics</subject><subject>Analgesics - analysis</subject><subject>Anti-Inflammatory Agents - analysis</subject><subject>Aquatic Pollution</subject><subject>Atmospheric Protection/Air Quality Control/Air Pollution</subject><subject>Diclofenac</subject><subject>Earth and Environmental Science</subject><subject>Ecotoxicology</subject><subject>Effluents</subject><subject>Environment</subject><subject>Environmental Chemistry</subject><subject>Environmental Health</subject><subject>Environmental Monitoring</subject><subject>Environmental risk</subject><subject>Environmental science</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Ibuprofen</subject><subject>Indomethacin</subject><subject>Inflammation</subject><subject>Inhabitants</subject><subject>Ketoprofen</subject><subject>Load</subject><subject>Mefenamic acid</subject><subject>Naproxen</subject><subject>Pharmaceutical Preparations</subject><subject>Pharmaceuticals</subject><subject>Research Article</subject><subject>Risk</subject><subject>Seasons</subject><subject>Summer</subject><subject>Toxicity</subject><subject>Toxicity testing</subject><subject>Trophic levels</subject><subject>Waste Disposal, Fluid</subject><subject>Waste Water - analysis</subject><subject>Waste Water Technology</subject><subject>Wastewater treatment</subject><subject>Wastewater treatment plants</subject><subject>Water Management</subject><subject>Water Pollutants, Chemical - analysis</subject><subject>Water Pollution Control</subject><subject>Winter</subject><issn>0944-1344</issn><issn>1614-7499</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kcFu1DAQhi0EotvCC3BAkbhwMczEjpMcUVUoUqteytkaeyetq8RZ7KRS3x5vdwGJAwdrJOubbzTzC_EO4RMCtJ8zomqMBOwlmK5GqV-IDRrUstV9_1JsoNdaotL6RJzm_ABQQ1-3r8WJwlY3HeiNGK7nGJY5hXhXLfdcJR6ZMlfzUFFcggxxGGmaqCBP5WdbHo13nIOvdveUJvK8LsHTmKsQjwbP4XHv4_gY0hwnjssb8WooDL891jPx4-vF7fmlvLr59v38y5X02uAiGyDjmAidM9w5cAax8Z32tWkUNaQ7Z3SzdYo7Ij0wq2Gre1KuhgFaZ9SZ-Hjw7tL8c-W82Clkz-NIkec121qh0aoFbAr64R_0YV5T2W5PKVSdMgiFqg-UT3POiQe7S2Gi9GQR7D4Fe0jBlhTscwpWl6b3R_XqJt7-afl99gKoA5B3-8tz-jv7P9pfqzyUDA</recordid><startdate>20191201</startdate><enddate>20191201</enddate><creator>Aydin, Senar</creator><creator>Aydin, Mehmet Emin</creator><creator>Ulvi, Arzu</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7SN</scope><scope>7T7</scope><scope>7TV</scope><scope>7U7</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>L.-</scope><scope>M0C</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>P64</scope><scope>PATMY</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20191201</creationdate><title>Monitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environment</title><author>Aydin, Senar ; Aydin, Mehmet Emin ; Ulvi, Arzu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-50a6beaa1bb6e8b0b6115c84c2653a5a48b645db3e8aa4fee3fd49a3b20f07b63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Acetaminophen</topic><topic>Algae</topic><topic>Analgesics</topic><topic>Analgesics - 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Academic</collection><jtitle>Environmental science and pollution research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aydin, Senar</au><au>Aydin, Mehmet Emin</au><au>Ulvi, Arzu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Monitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environment</atitle><jtitle>Environmental science and pollution research international</jtitle><stitle>Environ Sci Pollut Res</stitle><addtitle>Environ Sci Pollut Res Int</addtitle><date>2019-12-01</date><risdate>2019</risdate><volume>26</volume><issue>36</issue><spage>36887</spage><epage>36902</epage><pages>36887-36902</pages><issn>0944-1344</issn><eissn>1614-7499</eissn><abstract>The occurrence of anti-inflammatory and analgesic pharmaceuticals (AIAPs) in the effluents of 16 hospitals, influent and effluent of wastewater treatment plant (WWTP), the contribution and mass load of each hospital to WWTP influent, and the removal efficiencies in WWTP were investigated. Environmental risk was also evaluated by toxicity tests using organisms from three different trophic levels. Acetaminophen had the highest concentration in summer and winter samples, followed by ketoprofen, ibuprofen, and naproxen. The total daily load of AIAPs detected in influent of WWTP was 1677 mg/day/1000 inhabitants in summer and 5074 mg/day/1000 inhabitants in winter. The contribution of 16 hospitals to the total AIAP load in influent of WWTP was 11.30% in summer and 7.09% in winter. The highest mass loads were calculated as 203 mg/bed.day in general hospital in summer and 300 mg/bed.day in pediatric hospital in winter. The removal efficiencies of AIAPs in WWTP ranged between 13% and 100% in summer and 0.88% and 99% in winter. WWTP is not sufficient to remove all the AIAPs. Diclofenac (in summer), mefenamic acid, indomethacin, and phenylbutazone exhibited poor removal below 50%. The effluents of the WWTP exhibited a low risk for fish and
Daphnia magna
and an insignificant risk for algae.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>31745804</pmid><doi>10.1007/s11356-019-06821-4</doi><tpages>16</tpages></addata></record> |
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| subjects | Acetaminophen Algae Analgesics Analgesics - analysis Anti-Inflammatory Agents - analysis Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Diclofenac Earth and Environmental Science Ecotoxicology Effluents Environment Environmental Chemistry Environmental Health Environmental Monitoring Environmental risk Environmental science Hospitals Humans Ibuprofen Indomethacin Inflammation Inhabitants Ketoprofen Load Mefenamic acid Naproxen Pharmaceutical Preparations Pharmaceuticals Research Article Risk Seasons Summer Toxicity Toxicity testing Trophic levels Waste Disposal, Fluid Waste Water - analysis Waste Water Technology Wastewater treatment Wastewater treatment plants Water Management Water Pollutants, Chemical - analysis Water Pollution Control Winter |
| title | Monitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environment |
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