Oxytocin induced labor causes region and sex‐specific transient oligodendrocyte cell death in neonatal mouse brain

Aim Previous reports showed associations between oxytocin induced labor and mental disorders in offspring. However, those reports are restricted in epidemiological analyses and its mechanism remains unclear. In this study, we hypothesized that induced labor directly causes brain damage in newborns a...

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Veröffentlicht in:	The journal of obstetrics and gynaecology research 2020-01, Vol.46 (1), p.66-78
Hauptverfasser:	Hirayama, Takashi, Hiraoka, Yuichi, Kitamura, Eri, Miyazaki, Shinji, Horie, Kengo, Fukuda, Tomokazu, Hidema, Shizu, Koike, Masato, Itakura, Atsuo, Takeda, Satoru, Nishimori, Katsuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Apoptosis Brain damage Brain injury Cell death DNA nucleotidylexotransferase Epidemiology Fetuses Gene expression Glial fibrillary acidic protein Glial stem cells Induced labor JunB protein mental disorder Mental disorders Neonates Offspring Olig2 protein oligodendrocyte Oxytocin
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