TMTpro: Design, Synthesis, and Initial Evaluation of a Proline-Based Isobaric 16-Plex Tandem Mass Tag Reagent Set

The design and synthesis of a proline-based reporter isobaric Tandem Mass Tag structure (TMTpro) is presented. An analysis is made of the performance of the new TMTpro tags in comparison with the current commercially available dimethylpiperidine-reporter-based TMT10/11 reagents. The new reporter str...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Analytical chemistry (Washington) 2019-12, Vol.91 (24), p.15941-15950
Hauptverfasser:	Thompson, Andrew, Wölmer, Nikolai, Koncarevic, Sasa, Selzer, Stefan, Böhm, Gitte, Legner, Harald, Schmid, Peter, Kienle, Stefan, Penning, Petra, Höhle, Claudia, Berfelde, Antje, Martinez-Pinna, Roxana, Farztdinov, Vadim, Jung, Stephan, Kuhn, Karsten, Pike, Ian
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chemistry Heavy nuclei Mass spectrometers Missing data Proline Reagents Spectrometers Synthesis Tags
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!