Differential properties of mitosis-associated events following CHK1 and WEE1 inhibitor treatments in human tongue carcinoma cells

CHK1 and WEE1 play pivotal roles in G2/M checkpoint following exogenous DNA damage and regulation of DNA replication under normal cellular conditions. Here, we monitored and compared the cell cycle kinetics of mitosis-associated events after CHK1 and WEE1 inhibitor treatments in a human tongue cance...

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Veröffentlicht in:	Experimental cell research 2020-01, Vol.386 (2), p.111720-111720, Article 111720
Hauptverfasser:	Nojima, Hitomi, Homma, Hisao, Onozato, Yusuke, Kaida, Atsushi, Harada, Hiroyuki, Miura, Masahiko
Format:	Artikel
Sprache:	eng
Schlagworte:	CHK1 Endomitosis Fluorescent ubiquitination-based cell cycle indicator (Fucci) Spindle checkpoint WEE1
Online-Zugang:	Volltext
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