Link between personality and response to THC exposure

•The Sub-Dom mouse model demonstrates that the effect of THC is personality-dependent.•Dominant and submissive animals react differently to high and low doses of THC.•THC effect persists after a substantial period of drug cessation.•Personal traits should be considered when prescribing medical canna...

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Veröffentlicht in:	Behavioural brain research 2020-02, Vol.379, p.112361-112361, Article 112361
Hauptverfasser:	Kardash, Tetiana, Rodin, Dmitry, Kirby, Michael, Davis, Noa, Koman, Igor, Gorelick, Jonathan, Michaelevski, Izhak, Pinhasov, Albert
Format:	Artikel
Sprache:	eng
Schlagworte:	Addiction Animals Aversion Behavior Behavior, Animal - drug effects Cannabinoid Receptor Agonists - administration & dosage Cannabinoid Receptor Agonists - pharmacology Cannabis Conditioning, Psychological - drug effects Corticosterone - blood Depression - chemically induced Depression - drug therapy Disease Models, Animal Dominance-Subordination Dronabinol - administration & dosage Dronabinol - pharmacology Male Mice Personality Personality - physiology THC
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