Position Effect of Fatty Acid Modification on the Cytotoxicity and Antimetastasis Potential of the Cytotoxic Peptide Lycosin‑I

Peptide modification with fatty acids is an effective method to improve peptide performance. We previously investigated the fatty acid modification of R-lycosin-I, a cytotoxic peptide derived from lycosin-I from the venom of the spider Lycosa singoriensis. In this study, we further investigated the...

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Veröffentlicht in:Journal of medicinal chemistry 2019-12, Vol.62 (24), p.11108-11118
Hauptverfasser: Zhang, Peng, Jian, Cui, Jian, Shandong, Zhang, Qianqian, Sun, Xiaoliang, Nie, Liqin, Liu, Bobo, Li, Fengjiao, Li, Jinting, Liu, Meiyan, Liang, Songping, Zeng, Youlin, Liu, Zhonghua
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Sprache:eng
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