Study on the RBE estimation for carbon beam scanning irradiation using a solid‐state microdosimeter
Purpose The purpose of this study was to study the field size effect on the estimated Relative Biological Effectiveness (RBE) for carbon scanning beam irradiation. Methods A silicon‐on‐insulator (SOI) microdosimeter system developed by the Centre for Medical Radiation Physics, University of Wollongo...
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| Veröffentlicht in: | Medical physics (Lancaster) 2020-02, Vol.47 (2), p.363-370 |
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| creator | Han, Soorim Yoo, Seung Hoon Shin, Jae Ik Kim, Eun Ho Jung, Won‐Gyun Kim, Kum Bae Matsumura, Akihiko Kanai, Tatsuaki Tran, Linh T. Chartier, Lachlan James, Benjamin Rosenfeld, Anatoly B. |
| description | Purpose
The purpose of this study was to study the field size effect on the estimated Relative Biological Effectiveness (RBE) for carbon scanning beam irradiation.
Methods
A silicon‐on‐insulator (SOI) microdosimeter system developed by the Centre for Medical Radiation Physics, University of Wollongong, Australia, was used for lineal‐energy measurements (microdosimetric quantity). The RBE values were derived based on the modified microdosimetric kinetic model (MKM) at different depths in a water phantom in the scanning carbon beam for various scanned areas.
Results
Our study shows that the difference in RBE values derived from the SOI microdosimeter measurements with the MKM model and from the Treatment Planning System (TPS). The difference of the RBE values is within 6.5 % at the peak point of the spread‐out Bragg Peak (SOBP) region. Compared to the spot‐beam, RBE values obtained in the scanned‐beam with a larger scanned area of 1.0 × 1.0 cm2 have better agreement with which estimated by the TPS.
Conclusions
This study shows the possibility of using the SOI microdosimeter system as a quality assurance (QA) tool for RBE evaluation in carbon‐pencil beam scanning radiotherapy. |
| doi_str_mv | 10.1002/mp.13924 |
| format | Article |
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The purpose of this study was to study the field size effect on the estimated Relative Biological Effectiveness (RBE) for carbon scanning beam irradiation.
Methods
A silicon‐on‐insulator (SOI) microdosimeter system developed by the Centre for Medical Radiation Physics, University of Wollongong, Australia, was used for lineal‐energy measurements (microdosimetric quantity). The RBE values were derived based on the modified microdosimetric kinetic model (MKM) at different depths in a water phantom in the scanning carbon beam for various scanned areas.
Results
Our study shows that the difference in RBE values derived from the SOI microdosimeter measurements with the MKM model and from the Treatment Planning System (TPS). The difference of the RBE values is within 6.5 % at the peak point of the spread‐out Bragg Peak (SOBP) region. Compared to the spot‐beam, RBE values obtained in the scanned‐beam with a larger scanned area of 1.0 × 1.0 cm2 have better agreement with which estimated by the TPS.
Conclusions
This study shows the possibility of using the SOI microdosimeter system as a quality assurance (QA) tool for RBE evaluation in carbon‐pencil beam scanning radiotherapy.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1002/mp.13924</identifier><identifier>PMID: 31732963</identifier><language>eng</language><publisher>United States</publisher><subject>carbon scanning beam ; LET measurement ; RBE prediction ; SOI detector</subject><ispartof>Medical physics (Lancaster), 2020-02, Vol.47 (2), p.363-370</ispartof><rights>2019 American Association of Physicists in Medicine</rights><rights>2019 American Association of Physicists in Medicine.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3214-7da8cd762a62a56cb41f42cec84b8e732aa10d49556b44a83773cb5b2254a7be3</citedby><cites>FETCH-LOGICAL-c3214-7da8cd762a62a56cb41f42cec84b8e732aa10d49556b44a83773cb5b2254a7be3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmp.13924$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmp.13924$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31732963$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Han, Soorim</creatorcontrib><creatorcontrib>Yoo, Seung Hoon</creatorcontrib><creatorcontrib>Shin, Jae Ik</creatorcontrib><creatorcontrib>Kim, Eun Ho</creatorcontrib><creatorcontrib>Jung, Won‐Gyun</creatorcontrib><creatorcontrib>Kim, Kum Bae</creatorcontrib><creatorcontrib>Matsumura, Akihiko</creatorcontrib><creatorcontrib>Kanai, Tatsuaki</creatorcontrib><creatorcontrib>Tran, Linh T.</creatorcontrib><creatorcontrib>Chartier, Lachlan</creatorcontrib><creatorcontrib>James, Benjamin</creatorcontrib><creatorcontrib>Rosenfeld, Anatoly B.</creatorcontrib><title>Study on the RBE estimation for carbon beam scanning irradiation using a solid‐state microdosimeter</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>Purpose
The purpose of this study was to study the field size effect on the estimated Relative Biological Effectiveness (RBE) for carbon scanning beam irradiation.
Methods
A silicon‐on‐insulator (SOI) microdosimeter system developed by the Centre for Medical Radiation Physics, University of Wollongong, Australia, was used for lineal‐energy measurements (microdosimetric quantity). The RBE values were derived based on the modified microdosimetric kinetic model (MKM) at different depths in a water phantom in the scanning carbon beam for various scanned areas.
Results
Our study shows that the difference in RBE values derived from the SOI microdosimeter measurements with the MKM model and from the Treatment Planning System (TPS). The difference of the RBE values is within 6.5 % at the peak point of the spread‐out Bragg Peak (SOBP) region. Compared to the spot‐beam, RBE values obtained in the scanned‐beam with a larger scanned area of 1.0 × 1.0 cm2 have better agreement with which estimated by the TPS.
Conclusions
This study shows the possibility of using the SOI microdosimeter system as a quality assurance (QA) tool for RBE evaluation in carbon‐pencil beam scanning radiotherapy.</description><subject>carbon scanning beam</subject><subject>LET measurement</subject><subject>RBE prediction</subject><subject>SOI detector</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp1kMtKAzEUhoMotlbBJ5As3UzNdS5LLfUCFcXLOiSZjEYmM2Myg3TnI_iMPomprboSDpzDz8fP-X8ADjGaYoTIieummBaEbYExYRlNGEHFNhgjVLCEMMRHYC-EF4RQSjnaBSOKM0qKlI6Bue-HcgnbBvbPBt6dzaEJvXWyt1GqWg-19CqeykgHg5ZNY5snaL2XpV1DQ1gpEoa2tuXn-0foZW-gs9q3ZRusM73x-2CnknUwB5s9AY_n84fZZbK4ubianS4STQlmSVbKXJdZSmQcnmrFcMWINjpnKjfxZSkxKlnBeaoYkznNMqoVV4RwJjNl6AQcr307374OMYlwNmhT17Ix7RAEoZhjVHCG_9D4ZwjeVKLzMbdfCozEqlThOvFdakSPNq6Dcqb8BX9ajECyBt5sbZb_Gonr27XhF2GtgVE</recordid><startdate>202002</startdate><enddate>202002</enddate><creator>Han, Soorim</creator><creator>Yoo, Seung Hoon</creator><creator>Shin, Jae Ik</creator><creator>Kim, Eun Ho</creator><creator>Jung, Won‐Gyun</creator><creator>Kim, Kum Bae</creator><creator>Matsumura, Akihiko</creator><creator>Kanai, Tatsuaki</creator><creator>Tran, Linh T.</creator><creator>Chartier, Lachlan</creator><creator>James, Benjamin</creator><creator>Rosenfeld, Anatoly B.</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202002</creationdate><title>Study on the RBE estimation for carbon beam scanning irradiation using a solid‐state microdosimeter</title><author>Han, Soorim ; Yoo, Seung Hoon ; Shin, Jae Ik ; Kim, Eun Ho ; Jung, Won‐Gyun ; Kim, Kum Bae ; Matsumura, Akihiko ; Kanai, Tatsuaki ; Tran, Linh T. ; Chartier, Lachlan ; James, Benjamin ; Rosenfeld, Anatoly B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3214-7da8cd762a62a56cb41f42cec84b8e732aa10d49556b44a83773cb5b2254a7be3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>carbon scanning beam</topic><topic>LET measurement</topic><topic>RBE prediction</topic><topic>SOI detector</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Han, Soorim</creatorcontrib><creatorcontrib>Yoo, Seung Hoon</creatorcontrib><creatorcontrib>Shin, Jae Ik</creatorcontrib><creatorcontrib>Kim, Eun Ho</creatorcontrib><creatorcontrib>Jung, Won‐Gyun</creatorcontrib><creatorcontrib>Kim, Kum Bae</creatorcontrib><creatorcontrib>Matsumura, Akihiko</creatorcontrib><creatorcontrib>Kanai, Tatsuaki</creatorcontrib><creatorcontrib>Tran, Linh T.</creatorcontrib><creatorcontrib>Chartier, Lachlan</creatorcontrib><creatorcontrib>James, Benjamin</creatorcontrib><creatorcontrib>Rosenfeld, Anatoly B.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Han, Soorim</au><au>Yoo, Seung Hoon</au><au>Shin, Jae Ik</au><au>Kim, Eun Ho</au><au>Jung, Won‐Gyun</au><au>Kim, Kum Bae</au><au>Matsumura, Akihiko</au><au>Kanai, Tatsuaki</au><au>Tran, Linh T.</au><au>Chartier, Lachlan</au><au>James, Benjamin</au><au>Rosenfeld, Anatoly B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Study on the RBE estimation for carbon beam scanning irradiation using a solid‐state microdosimeter</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2020-02</date><risdate>2020</risdate><volume>47</volume><issue>2</issue><spage>363</spage><epage>370</epage><pages>363-370</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><abstract>Purpose
The purpose of this study was to study the field size effect on the estimated Relative Biological Effectiveness (RBE) for carbon scanning beam irradiation.
Methods
A silicon‐on‐insulator (SOI) microdosimeter system developed by the Centre for Medical Radiation Physics, University of Wollongong, Australia, was used for lineal‐energy measurements (microdosimetric quantity). The RBE values were derived based on the modified microdosimetric kinetic model (MKM) at different depths in a water phantom in the scanning carbon beam for various scanned areas.
Results
Our study shows that the difference in RBE values derived from the SOI microdosimeter measurements with the MKM model and from the Treatment Planning System (TPS). The difference of the RBE values is within 6.5 % at the peak point of the spread‐out Bragg Peak (SOBP) region. Compared to the spot‐beam, RBE values obtained in the scanned‐beam with a larger scanned area of 1.0 × 1.0 cm2 have better agreement with which estimated by the TPS.
Conclusions
This study shows the possibility of using the SOI microdosimeter system as a quality assurance (QA) tool for RBE evaluation in carbon‐pencil beam scanning radiotherapy.</abstract><cop>United States</cop><pmid>31732963</pmid><doi>10.1002/mp.13924</doi><tpages>8</tpages></addata></record> |
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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
| subjects | carbon scanning beam LET measurement RBE prediction SOI detector |
| title | Study on the RBE estimation for carbon beam scanning irradiation using a solid‐state microdosimeter |
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