Epigenetic silencing of microRNA-335 contributes to nasopharyngeal carcinoma metastasis

MircoRNA-335 (miR-335), a member of mircoRNAs (miRNAs) family, has been found to be correlated with tumor invasion and metastasis. In this study, we aimed to detect the effect of miR-335 methylation on metastasis of nasopharyngeal carcinoma. RT-PCR and methylation-specific PCR were applied to detect...

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Veröffentlicht in:	American journal of otolaryngology 2020-01, Vol.41 (1), p.102302-102302, Article 102302
Hauptverfasser:	Yang, Ju-hong, Lin, Lie-Kun, Zhang, Song
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Cancer Deoxyribonucleic acid DNA DNA methylation Epigenesis, Genetic Epigenetics Experiments Gene expression Gene Silencing Head & neck cancer Humans Lymph nodes Lymphatic system Metastases Metastasis Methylation MicroRNAs MicroRNAs - genetics miR-335 miRNA Nasopharyngeal carcinoma Nasopharyngeal Carcinoma - genetics Nasopharyngeal Carcinoma - pathology Neoplasm Metastasis - genetics Neoplasm Staging Patients Polymerase chain reaction Ribonucleic acid RNA Throat cancer Tissues Tumors
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