11-β-hydroxysterols as possible endogenous stimulators of mitochondrial biogenesis as inferred from epicatechin molecular mimicry

[Display omitted] Currently, there is great interest in identifying endogenous (i.e. physiological) stimulators of mitochondrial biogenesis (MB), in particular, those that may mediate the effects of exercise. The molecular size of the cacao flavanols (epicatechin and catechin) highly resembles that...

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Veröffentlicht in:	Pharmacological research 2020-01, Vol.151, p.104540-104540, Article 104540
Hauptverfasser:	Dugar, Sundeep, Villarreal, Francisco, Hollinger, Frank H., Mahajan, Dinesh, Ramirez-Sanchez, Israel, Moreno-Ulloa, Aldo, Ceballos, Guillermo, Schreiner, George
Format:	Artikel
Sprache:	eng
Schlagworte:	11-β-hydroxypregnenolone Animals Catechin - chemistry Catechin - pharmacology Cattle Cell Line Cells, Cultured Epicatechin Mice Mitochondrial biogenesis Models, Molecular Molecular Mimicry Organelle Biogenesis Stereoisomerism Steroids Sterols - chemistry Sterols - pharmacology
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