Association of global DNA hypomethylation with post‐operative cognitive dysfunction in elderly patients undergoing hip surgery

Background Post‐operative cognitive dysfunction (POCD) is a decline of cognitive status that commonly occurs after surgery in elderly patients. Whether DNA methylation is associated with the development of POCD remains unclear. Methods Subjects (N = 124) older than 65 years‐of‐age undergoing hip rep...

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Veröffentlicht in:	Acta anaesthesiologica Scandinavica 2020-03, Vol.64 (3), p.354-360
Hauptverfasser:	Li, Hui, Wu, Ting‐Ting, Tang, Lin, Liu, Qing, Mao, Xin‐zhan, Xu, Jun‐mei, Dai, Ru‐Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	5‐methylcytosine Anesthesia Bivariate analysis Cognitive ability Deoxyribonucleic acid DNA DNA methylation epigenetics Geriatrics global DNA methylation Hip Indexing leukocyte Levels Older people post‐operative cognitive dysfunction Surgery
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