Immunohistochemistry for the detection of BRCA1 and BRCA2 proteins in patients with ovarian cancer: a systematic review

BackgroundLoss of function in either breast cancer type 1 susceptibility protein (BRCA1) or breast cancer type 2 susceptibility protein (BRCA2) is a major risk factor for epithelial ovarian cancer (EOC) development. BRCA1 or BRCA2 deficiencies are associated with short-term prognosis and might have...

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Veröffentlicht in:	Journal of clinical pathology 2020-04, Vol.73 (4), p.191-196
Hauptverfasser:	Teixeira, Lorena Alves, Candido dos Reis, Francisco Jose
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - metabolism BRCA1 Protein - immunology BRCA1 Protein - metabolism BRCA2 Protein - immunology BRCA2 Protein - metabolism Breast cancer carcinoma Female Grey literature Gynecology Humans Immunoglobulins Immunohistochemistry Obstetrics Ovarian cancer Ovarian Neoplasms - mortality ovarian tumour Protein expression Proteins Review Risk Factors Studies Systematic review Tumors
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