Mirabegron Add-on Therapy to Tamsulosin for the Treatment of Overactive Bladder in Men with Lower Urinary Tract Symptoms: A Randomized, Placebo-controlled Study (MATCH)

Men with lower urinary tract symptoms (LUTS) treated with α-blockers (eg, tamsulosin) may experience overactive bladder (OAB) symptoms and receive add-on antimuscarinics. Mirabegron (a β3-adrenoreceptor agonist) is an alternative add-on therapy. To evaluate the efficacy of mirabegron versus placebo...

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Veröffentlicht in:	European urology focus 2020-07, Vol.6 (4), p.729-737
Hauptverfasser:	Kakizaki, Hidehiro, Lee, Kyu-Sung, Yamamoto, Osamu, Jong, Jar Jar, Katou, Daisuke, Sumarsono, Budiwan, Uno, Satoshi, Yamaguchi, Osamu
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetanilides - administration & dosage Adrenergic alpha-1 Receptor Antagonists - administration & dosage Adrenergic beta-3 Receptor Agonists - administration & dosage Aged Combination therapy Double-Blind Method Drug Therapy, Combination Efficacy Humans Lower Urinary Tract Symptoms - complications Lower Urinary Tract Symptoms - drug therapy Male Middle Aged Mirabegron Overactive bladder Single-Blind Method Tamsulosin Tamsulosin - administration & dosage Thiazoles - administration & dosage Tolerability Treatment Outcome Urinary Bladder, Overactive - complications Urinary Bladder, Overactive - drug therapy α-Blocker
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