Guanylate-binding protein 6 is a novel biomarker for tumorigenesis and prognosis in tongue squamous cell carcinoma

Objectives Guanylate-binding protein 6 (GBP6) is a member of the guanylate-binding protein family, and its role in cancer has not yet been reported. We aimed to investigate the clinical significance of GBP6 in oral squamous cell carcinoma (OSCC). Materials and methods Next-generation sequencing was...

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Veröffentlicht in:	Clinical oral investigations 2020-08, Vol.24 (8), p.2673-2682
Hauptverfasser:	Liu, Pei-Feng, Chen, Hung-Chih, Shu, Chih-Wen, Sie, Huei-Cin, Lee, Cheng-Hsin, Liou, Huei-Han, Cheng, Jiin-Tsuey, Tsai, Kuo-Wang, Ger, Luo-Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Buccal mucosa Cell differentiation Dentistry Gene expression Guanylate-binding protein Immunohistochemistry Lymph nodes Medical prognosis Medicine Metastases Next-generation sequencing Oral cancer Oral squamous cell carcinoma Original Article Polymerase chain reaction Prognosis Protein expression Proteins Squamous cell carcinoma Tongue Tumorigenesis
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