Regulation of Pyruvate Formate Lyase-Deficient Klebsiella pneumoniae for Efficient 1,3-Propanediol Bioproduction

Anaerobic growth defect of pyruvate formate lyase (PFL)-deficient Klebsiella pneumoniae limits its industrial application, and the reason for this growth defect was analyzed in this study. The obtained evidences, combined with normal intracellular redox status and no further inhibition by adhE delet...

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Veröffentlicht in:	Current microbiology 2020, Vol.77 (1), p.55-61
Hauptverfasser:	Bao, Wenjing, Wei, Renquan, Liu, Xuxia, Dong, Shufan, Chen, Tianyu, Fu, Shuilin, Gong, Heng
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3-Propanediol Acetic acid Batch culture Biomedical and Life Sciences Biotechnology Butanediol Clonal deletion Defects Fermentation Gene deletion Gene expression Industrial applications Klebsiella Klebsiella pneumoniae Life Sciences Microbiology Pyruvic acid Transcription
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