Moxifloxacin resistance and genotyping of Mycobacterium avium and Mycobacterium intracellulare isolates in Japan

Although fluoroquinolones are considered as alternative therapies of pulmonary Mycobacterium avium complex (MAC) disease, the association between fluoroquinolone resistance and MAC genotypes in clinical isolates from individuals not previously treated for MAC infection is not fully clear. Totals of...

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Veröffentlicht in:	Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2019-12, Vol.25 (12), p.995-1000
Hauptverfasser:	Yamaba, Yusuke, Ito, Yutaka, Suzuki, Katsuhiro, Kikuchi, Toshiaki, Ogawa, Kenji, Fujiuchi, Satoru, Hasegawa, Naoki, Kurashima, Atsuyuki, Higuchi, Takeshi, Uchiya, Kei-ichi, Watanabe, Akira, Niimi, Akio
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use DNA Gyrase - genetics Drug Resistance, Bacterial - genetics Genotype gyrA gyrB Humans Japan Microbial Sensitivity Tests Minisatellite Repeats - genetics Moxifloxacin Moxifloxacin - pharmacology Moxifloxacin - therapeutic use Mutation Mycobacterium avium - drug effects Mycobacterium avium - genetics Mycobacterium avium - isolation & purification Mycobacterium avium complex Mycobacterium avium Complex - drug effects Mycobacterium avium Complex - genetics Mycobacterium avium Complex - isolation & purification Mycobacterium avium-intracellulare Infection - drug therapy Mycobacterium avium-intracellulare Infection - microbiology Variable numbers of tandem repeats
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