N-acetyl-l-cysteine protects porcine oocytes undergoing meiotic resumption from heat stress

•GVBD oocytes undergoing meiotic resumption are much sensitive to HS.•GVBD-specific HS disorganizes oocyte spindle assembly and inhibits ERK signaling.•GVBD-specific HS induces erroneous H3K27me3 modification in oocytes.•NAC protects oocyte cellular and molecular events against GVBD-specific HS.•NAC...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Reproductive toxicology (Elmsford, N.Y.) N.Y.), 2020-01, Vol.91, p.27-34
Hauptverfasser:	Hu, Xiao, Cheng, Linghua, Wang, Xiaodong, Luo, Gang, Zhao, Tianqing, Tian, Jianhui, An, Lei
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine - pharmacology Animals Apoptosis Embryonic development Female Heat stress Heat-Shock Response In Vitro Oocyte Maturation Techniques Life Sciences & Biomedicine Meiosis N-acetyl-l-cysteine Oocyte maturation Oocytes - cytology Oocytes - drug effects Oocytes - metabolism Oxidative Stress Porcine oocytes Protective Agents - pharmacology Reactive Oxygen Species - metabolism Reproductive Biology Science & Technology Swine Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!