Eosinophil extracellular traps activate type 2 innate lymphoid cells through stimulating airway epithelium in severe asthma

Background Activated eosinophils release extracellular traps (EETs), which contribute to airway inflammation in severe asthma (SA). However, the role of EETs in innate immunity has not yet been completely determined. The present study aimed to demonstrate the mechanism of airway inflammation in SA m...

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Veröffentlicht in:	Allergy (Copenhagen) 2020-01, Vol.75 (1), p.95-103
Hauptverfasser:	Choi, Youngwoo, Kim, Young‐Min, Lee, Hee‐Ra, Mun, Jiyeong, Sim, Soyoon, Lee, Dong‐Hyun, Pham, Duy Le, Kim, Seung‐Hyun, Shin, Yoo Seob, Lee, Seung‐Woo, Park, Hae‐Sim
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alveoli Animals Asthma Asthma - immunology Bronchus eosinophils Eosinophils - immunology Epithelium extracellular traps Extracellular Traps - immunology Female Humans Immune response Innate immunity innate lymphoid cells Leukocytes (eosinophilic) Lymphocyte Subsets - immunology Lymphocytes - immunology Lymphoid cells Male Mice Mice, Inbred BALB C Middle Aged RAG1 protein Respiratory Mucosa - immunology Respiratory tract Respiratory tract diseases severe asthma Thymic stromal lymphopoietin Traps
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