Evidence for a Contribution of the Nlgn3/Cyfip1/Fmr1 Pathway in the Pathophysiology of Autism Spectrum Disorders

Autism Spectrum Disorders (ASD) are characterized by heterogeneity both in their presentation and their genetic aetiology. In order to discover points of convergence common to different cases of ASD, attempts were made to identify the biological pathways genes associated with ASD contribute to. Many...

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Veröffentlicht in:	Neuroscience 2020-10, Vol.445, p.31-41
Hauptverfasser:	Sledziowska, Monika, Galloway, James, Baudouin, Stéphane J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Animals Autism Spectrum Disorder Autism Spectrum Disorder - genetics Carrier Proteins Cell Adhesion Molecules, Neuronal - genetics Cyfip1 Disease Models, Animal Fragile X Mental Retardation Protein - genetics Fragile-X Humans Membrane Proteins - genetics Mice mouse models Nerve Tissue Proteins - genetics Neuroligin Neuronal Plasticity Phenotype
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