SUMOylation homeostasis in tumorigenesis

Small ubiquitin-like modifier (SUMO), a critical regulatory modification protein, is involved in various biological processes, such as gene expression, genome maintenance and DNA damage repair (DDR). Numerous recent studies have revealed that disturbed SUMOylation and deSUMOylation homeostasis contr...

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Veröffentlicht in:	Cancer letters 2020-01, Vol.469, p.301-309
Hauptverfasser:	Xie, Minyue, Yu, Jie, Ge, Shengfang, Huang, Jian, Fan, Xianqun
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Cell cycle Colorectal cancer Deoxyribonucleic acid DNA DNA damage DNA repair Enzymes Gene expression Genomes Homeostasis Kinases Leukemia Liver cancer Localization Maintenance Prostate cancer Proteins SUMO protein SUMOylation Tumorigenesis Ubiquitin
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