Quantifying functional impact of non-coding variants with multi-task Bayesian neural network

Abstract Motivation Advances in high-throughput genotyping and sequencing technologies during recent years have revealed essential roles of non-coding regions in gene regulation. Genome-wide association studies (GWAS) suggested that a large proportion of risk variants are located in non-coding regio...

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Veröffentlicht in:Bioinformatics 2020-03, Vol.36 (5), p.1397-1404
Hauptverfasser: Xu, Chencheng, Liu, Qiao, Zhou, Jianyu, Xie, Minzhu, Feng, Jianxing, Jiang, Tao
Format: Artikel
Sprache:eng
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