How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion
Aim To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer. Patients and Methods We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes. Results Of 447 patients, 82.6% underwent D2...
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| Veröffentlicht in: | Journal of gastrointestinal cancer 2020-09, Vol.51 (3), p.887-892 |
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| creator | Rausei, Stefano Galli, Federica Lianos, Georgios Rosa, Fausto Cossu, Andrea Biondi, Alberto Martignoni, Francesco Cananzi, Ferdinando Carlo Maria Fumagalli, Uberto Alfieri, Sergio Persiani, Roberto Quagliuolo, Vittorio D’Ugo, Domenico Rosati, Riccardo |
| description | Aim
To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer.
Patients and Methods
We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes.
Results
Of 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%;
p
< 0.001) and between patients with total examined lymph nodes ≥ 28 and < 28 (74.5% versus 62.3%;
p
= 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter.
Conclusion
We should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer. |
| doi_str_mv | 10.1007/s12029-019-00321-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2312550871</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2312550871</sourcerecordid><originalsourceid>FETCH-LOGICAL-c347t-4d974535439e0f69ff2f5b45dfae805ec32517abd2b82ab990d6473c86d3e2653</originalsourceid><addsrcrecordid>eNp9kMtLxDAQxoMovv8BD5Kjl2oeTdqeRBZfsCri6xjSdOJW2mZNGtz9742uevQwzDDfNx_MD6EDSo4pIcVJoIywKiM0FeGMZos1tE2rnGZScrn-N7NyC-2E8EaIzAWlm2iLU1lRUhbbaLhyH_hh5mLX4BfAN6BD9IDHGeD7qLt2XGJn8XTZz2e6gQHM6Polts7jSx1G3xo80YMBf4rPBp201ugOP4MPMeDb2IP_Xkx8O6bRDXtow-ouwP5P30VPF-ePk6tsend5PTmbZobnxZjlTVXkgoucV0CsrKxlVtS5aKyGkggwnAla6Lphdcl0XVWkkXnBTSkbDkwKvouOVrlz794jhFH1bTDQdXoAF4NinDIhEgGarGxlNd6F4MGquW977ZeKEvXFWa04q8RZfXNWi3R0-JMf6x6av5NfsMnAV4aQpOEVvHpz0Q_p5_9iPwENm4m8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2312550871</pqid></control><display><type>article</type><title>How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Rausei, Stefano ; Galli, Federica ; Lianos, Georgios ; Rosa, Fausto ; Cossu, Andrea ; Biondi, Alberto ; Martignoni, Francesco ; Cananzi, Ferdinando Carlo Maria ; Fumagalli, Uberto ; Alfieri, Sergio ; Persiani, Roberto ; Quagliuolo, Vittorio ; D’Ugo, Domenico ; Rosati, Riccardo</creator><creatorcontrib>Rausei, Stefano ; Galli, Federica ; Lianos, Georgios ; Rosa, Fausto ; Cossu, Andrea ; Biondi, Alberto ; Martignoni, Francesco ; Cananzi, Ferdinando Carlo Maria ; Fumagalli, Uberto ; Alfieri, Sergio ; Persiani, Roberto ; Quagliuolo, Vittorio ; D’Ugo, Domenico ; Rosati, Riccardo</creatorcontrib><description>Aim
To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer.
Patients and Methods
We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes.
Results
Of 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%;
p
< 0.001) and between patients with total examined lymph nodes ≥ 28 and < 28 (74.5% versus 62.3%;
p
= 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter.
Conclusion
We should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.</description><identifier>ISSN: 1941-6628</identifier><identifier>EISSN: 1941-6636</identifier><identifier>DOI: 10.1007/s12029-019-00321-x</identifier><identifier>PMID: 31691087</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adenocarcinoma - pathology ; Adenocarcinoma - surgery ; Adult ; Aged ; Aged, 80 and over ; Cancer Research ; Female ; Follow-Up Studies ; Gastrectomy - methods ; Gastroenterology ; Humans ; Internal Medicine ; Lymph Node Excision - methods ; Lymph Nodes - pathology ; Lymph Nodes - surgery ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Oncology ; Original Research ; Prognosis ; Quality Assurance, Health Care - statistics & numerical data ; Radiotherapy ; Retrospective Studies ; Stomach Neoplasms - pathology ; Stomach Neoplasms - surgery ; Survival Rate</subject><ispartof>Journal of gastrointestinal cancer, 2020-09, Vol.51 (3), p.887-892</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-4d974535439e0f69ff2f5b45dfae805ec32517abd2b82ab990d6473c86d3e2653</citedby><cites>FETCH-LOGICAL-c347t-4d974535439e0f69ff2f5b45dfae805ec32517abd2b82ab990d6473c86d3e2653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12029-019-00321-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12029-019-00321-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31691087$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rausei, Stefano</creatorcontrib><creatorcontrib>Galli, Federica</creatorcontrib><creatorcontrib>Lianos, Georgios</creatorcontrib><creatorcontrib>Rosa, Fausto</creatorcontrib><creatorcontrib>Cossu, Andrea</creatorcontrib><creatorcontrib>Biondi, Alberto</creatorcontrib><creatorcontrib>Martignoni, Francesco</creatorcontrib><creatorcontrib>Cananzi, Ferdinando Carlo Maria</creatorcontrib><creatorcontrib>Fumagalli, Uberto</creatorcontrib><creatorcontrib>Alfieri, Sergio</creatorcontrib><creatorcontrib>Persiani, Roberto</creatorcontrib><creatorcontrib>Quagliuolo, Vittorio</creatorcontrib><creatorcontrib>D’Ugo, Domenico</creatorcontrib><creatorcontrib>Rosati, Riccardo</creatorcontrib><title>How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion</title><title>Journal of gastrointestinal cancer</title><addtitle>J Gastrointest Canc</addtitle><addtitle>J Gastrointest Cancer</addtitle><description>Aim
To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer.
Patients and Methods
We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes.
Results
Of 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%;
p
< 0.001) and between patients with total examined lymph nodes ≥ 28 and < 28 (74.5% versus 62.3%;
p
= 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter.
Conclusion
We should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.</description><subject>Adenocarcinoma - pathology</subject><subject>Adenocarcinoma - surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cancer Research</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastrectomy - methods</subject><subject>Gastroenterology</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Lymph Node Excision - methods</subject><subject>Lymph Nodes - pathology</subject><subject>Lymph Nodes - surgery</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Oncology</subject><subject>Original Research</subject><subject>Prognosis</subject><subject>Quality Assurance, Health Care - statistics & numerical data</subject><subject>Radiotherapy</subject><subject>Retrospective Studies</subject><subject>Stomach Neoplasms - pathology</subject><subject>Stomach Neoplasms - surgery</subject><subject>Survival Rate</subject><issn>1941-6628</issn><issn>1941-6636</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtLxDAQxoMovv8BD5Kjl2oeTdqeRBZfsCri6xjSdOJW2mZNGtz9742uevQwzDDfNx_MD6EDSo4pIcVJoIywKiM0FeGMZos1tE2rnGZScrn-N7NyC-2E8EaIzAWlm2iLU1lRUhbbaLhyH_hh5mLX4BfAN6BD9IDHGeD7qLt2XGJn8XTZz2e6gQHM6Polts7jSx1G3xo80YMBf4rPBp201ugOP4MPMeDb2IP_Xkx8O6bRDXtow-ouwP5P30VPF-ePk6tsend5PTmbZobnxZjlTVXkgoucV0CsrKxlVtS5aKyGkggwnAla6Lphdcl0XVWkkXnBTSkbDkwKvouOVrlz794jhFH1bTDQdXoAF4NinDIhEgGarGxlNd6F4MGquW977ZeKEvXFWa04q8RZfXNWi3R0-JMf6x6av5NfsMnAV4aQpOEVvHpz0Q_p5_9iPwENm4m8</recordid><startdate>20200901</startdate><enddate>20200901</enddate><creator>Rausei, Stefano</creator><creator>Galli, Federica</creator><creator>Lianos, Georgios</creator><creator>Rosa, Fausto</creator><creator>Cossu, Andrea</creator><creator>Biondi, Alberto</creator><creator>Martignoni, Francesco</creator><creator>Cananzi, Ferdinando Carlo Maria</creator><creator>Fumagalli, Uberto</creator><creator>Alfieri, Sergio</creator><creator>Persiani, Roberto</creator><creator>Quagliuolo, Vittorio</creator><creator>D’Ugo, Domenico</creator><creator>Rosati, Riccardo</creator><general>Springer US</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20200901</creationdate><title>How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion</title><author>Rausei, Stefano ; Galli, Federica ; Lianos, Georgios ; Rosa, Fausto ; Cossu, Andrea ; Biondi, Alberto ; Martignoni, Francesco ; Cananzi, Ferdinando Carlo Maria ; Fumagalli, Uberto ; Alfieri, Sergio ; Persiani, Roberto ; Quagliuolo, Vittorio ; D’Ugo, Domenico ; Rosati, Riccardo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c347t-4d974535439e0f69ff2f5b45dfae805ec32517abd2b82ab990d6473c86d3e2653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adenocarcinoma - pathology</topic><topic>Adenocarcinoma - surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cancer Research</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gastrectomy - methods</topic><topic>Gastroenterology</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Lymph Node Excision - methods</topic><topic>Lymph Nodes - pathology</topic><topic>Lymph Nodes - surgery</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Oncology</topic><topic>Original Research</topic><topic>Prognosis</topic><topic>Quality Assurance, Health Care - statistics & numerical data</topic><topic>Radiotherapy</topic><topic>Retrospective Studies</topic><topic>Stomach Neoplasms - pathology</topic><topic>Stomach Neoplasms - surgery</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rausei, Stefano</creatorcontrib><creatorcontrib>Galli, Federica</creatorcontrib><creatorcontrib>Lianos, Georgios</creatorcontrib><creatorcontrib>Rosa, Fausto</creatorcontrib><creatorcontrib>Cossu, Andrea</creatorcontrib><creatorcontrib>Biondi, Alberto</creatorcontrib><creatorcontrib>Martignoni, Francesco</creatorcontrib><creatorcontrib>Cananzi, Ferdinando Carlo Maria</creatorcontrib><creatorcontrib>Fumagalli, Uberto</creatorcontrib><creatorcontrib>Alfieri, Sergio</creatorcontrib><creatorcontrib>Persiani, Roberto</creatorcontrib><creatorcontrib>Quagliuolo, Vittorio</creatorcontrib><creatorcontrib>D’Ugo, Domenico</creatorcontrib><creatorcontrib>Rosati, Riccardo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of gastrointestinal cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rausei, Stefano</au><au>Galli, Federica</au><au>Lianos, Georgios</au><au>Rosa, Fausto</au><au>Cossu, Andrea</au><au>Biondi, Alberto</au><au>Martignoni, Francesco</au><au>Cananzi, Ferdinando Carlo Maria</au><au>Fumagalli, Uberto</au><au>Alfieri, Sergio</au><au>Persiani, Roberto</au><au>Quagliuolo, Vittorio</au><au>D’Ugo, Domenico</au><au>Rosati, Riccardo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion</atitle><jtitle>Journal of gastrointestinal cancer</jtitle><stitle>J Gastrointest Canc</stitle><addtitle>J Gastrointest Cancer</addtitle><date>2020-09-01</date><risdate>2020</risdate><volume>51</volume><issue>3</issue><spage>887</spage><epage>892</epage><pages>887-892</pages><issn>1941-6628</issn><eissn>1941-6636</eissn><abstract>Aim
To compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer.
Patients and Methods
We analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes.
Results
Of 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%;
p
< 0.001) and between patients with total examined lymph nodes ≥ 28 and < 28 (74.5% versus 62.3%;
p
= 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter.
Conclusion
We should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>31691087</pmid><doi>10.1007/s12029-019-00321-x</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1941-6628 |
| ispartof | Journal of gastrointestinal cancer, 2020-09, Vol.51 (3), p.887-892 |
| issn | 1941-6628 1941-6636 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2312550871 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Adenocarcinoma - pathology Adenocarcinoma - surgery Adult Aged Aged, 80 and over Cancer Research Female Follow-Up Studies Gastrectomy - methods Gastroenterology Humans Internal Medicine Lymph Node Excision - methods Lymph Nodes - pathology Lymph Nodes - surgery Male Medicine Medicine & Public Health Middle Aged Oncology Original Research Prognosis Quality Assurance, Health Care - statistics & numerical data Radiotherapy Retrospective Studies Stomach Neoplasms - pathology Stomach Neoplasms - surgery Survival Rate |
| title | How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion |
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