Homogeneous Oligomeric Ligands Prepared via Radical Polymerization that Recognize and Neutralize a Target Peptide

Abiotic ligands that bind to specific biomolecules have attracted attention as substitutes for biomolecular ligands, such as antibodies and aptamers. Radical polymerization enables the production of robust polymeric ligands from inexpensive functional monomers. However, little has been reported abou...

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Veröffentlicht in:	Angewandte Chemie International Edition 2020-01, Vol.59 (2), p.679-683
Hauptverfasser:	Hoshino, Yu, Taniguchi, Shohei, Takimoto, Hinata, Akashi, Sotaro, Katakami, Sho, Yonamine, Yusuke, Miura, Yoshiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Aptamers Biomolecules block copolymers combinatorial chemistry Epitopes Functional groups homogeneous oligomer Humans Ligands Monomers Oligomers Peptides Peptides - chemistry Polymerization synthetic ligand Target recognition Toxicity
Online-Zugang:	Volltext
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